ArticleDiabetes care2012
Effect of diabetes on severity and hospital mortality in patients with acute pancreatitis: a national population-based study.
Article in Diabetes care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Preexisting Diabetes Elevates Risk of Local and Systemic Complications in Acute Pancreatitis: Systematic Review and Meta-analysis.Pancreas · 2018Pooled it
- Development and interpretable machine learning models for classification of pancreatic pseudocyst risk in acute pancreatitis.Frontiers in digital health · 2026Article
- The effect of blood glucose levels on serum triglyceride clearance in patients with hyperlipidemic acute pancreatitis.Scientific reports · 2025Article
- Correlation of hyperglycemia and balthazar classification in patients with acute pancreatitis.Pakistan journal of medical sciences · 2024Article
- Acute Pancreatitis and Type 2 Diabetes Mellitus: The Chicken-Egg Paradox-A Seven-Year Experience of a Large Tertiary Center.Journal of clinical medicine · 2024Article
- Clinical Outcomes of Diabetes Mellitus on Moderately Severe Acute Pancreatitis and Severe Acute Pancreatitis.Journal of inflammation research · 2024Article
- Stress Hyperglycemia Is Independently Associated with Persistent Organ Failure in Acute Pancreatitis.Digestive diseases and sciences · 2022Article
- Necrotizing Pancreatitis from Hypertriglyceridemia: More Severe Disease?Digestive diseases and sciences · 2021Article
- Leukocyte cell population data from the blood cell analyzer as a predictive marker for severity of acute pancreatitis.Journal of clinical laboratory analysis · 2021Article
- Domino effect of pituitary growth hormone tumor complicated by diabetic ketoacidosis and pituitary apoplexy: a case report.BMC endocrine disorders · 2021Article
- Article
- Class III obesity rather than metabolic syndrome impacts clinical outcomes of acute pancreatitis: A propensity score weighted analysis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2020Article
- Multifactorial Scores and Biomarkers of Prognosis of Acute Pancreatitis: Applications to Research and Practice.International journal of molecular sciences · 2020Review
- Risk factors for mortality in emphysematous pancreatitis.Journal of drug assessment · 2020Article
- HOMA-estimated insulin resistance as an independent prognostic factor in patients with acute pancreatitis.Scientific reports · 2019Article
- Risk factors for pancreatitis following endoscopic retrograde cholangiopancreatography.BJS open · 2019Article
- Relationships between Metabolic Comorbidities and Occurrence, Severity, and Outcomes in Patients with Acute Pancreatitis: A Narrative Review.BioMed research international · 2019Review
- Effect of JAK2/STAT3 signaling pathway on liver injury associated with severe acute pancreatitis in rats.Experimental and therapeutic medicine · 2018Article
- The sociocultural effects on orthopedic surgeries in Taiwan.PloS one · 2018Article
- MiR-133a Mimic Alleviates T1DM-Induced Systolic Dysfunction in Akita: An MRI-Based Study.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDiabetes may increase the risk of acute pancreatitis (AP). We aimed to further investigate whether diabetes may also adversely affect outcomes of patients with AP. RESEARCH DESIGN AND
methodsIn this retrospective cohort study, we compared 18,990 first-attack AP with diabetes to 37,980 matched control subjects from Taiwan's National Health Insurance Research Database between 2000 and 2009. Primary outcomes were development of severe AP, defined by a modified Atlanta classification scheme, and hospital mortality. Analyses were performed using univariable and multivariable logistic regression model with generalized estimating equations accounting for hospital clustering effect.
resultsAfter baseline characteristics were adjusted, AP patients with diabetes had a higher risk of a severe attack than their nondiabetic counterparts (adjusted odds ratio [OR] 1.21, 95% CI 1.16-1.26). When severity criteria were analyzed individually, diabetic AP patients had a 58% higher risk of intensive care unit admission and a 30% higher risk of local complications, but a 16% lower risk of gastrointestinal bleeding, than AP patients without diabetes. The risk of organ failure at least one system) was similar between the two groups. Conversely, AP patients with diabetes were associated with a lower risk of hospital mortality (adjusted OR 0.77, 95% CI 0.65-0.91).
conclusionsAlthough diabetes may adversely affect the disease process of AP, it seems to protect patients from AP-related mortality.
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