Evidence map›Paper›PMID 22445028›Full record

ArticleHealth & place2012

Neighborhood deprivation and clinical outcomes among head and neck cancer patients.

Lorraine R Reitzel, Nga Nguyen, Mark E Zafereo, Guojun Li, Qingyi Wei, Erich M Sturgis

Abstract read
In one paragraph

Article in Health & place, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Increased Rates of Unplanned Return to the Operating Room in Socioeconomically Deprived Orthopaedic Trauma Patient Populations.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  10. Article
  11. Social Genomic Determinants of Health: Understanding the Molecular Pathways by Which Neighborhood Disadvantage Affects Cancer Outcomes.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  12. Article
  13. The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. European white paper: oropharyngeal dysphagia in head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorraine R ReitzelDepartment of Health Disparities Research-Unit 1440, PO Box 301402, University of Texas MD Anderson Cancer Center, Houston, Texas 77230-1402, USA. Lrreitze@mdanderson.org
Nga Nguyen
Mark E Zafereo
Guojun Li
Qingyi Wei
Erich M Sturgis

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Molecular Epidemiology of Head and Neck CancerR01ES011740 · NIEHS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WEI, QINGYI · 2001 to 2012
$6.3M
Genotypes and Phenotypes of Apoptosis and Risk of Head and Neck CancerR01CA131274 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WEI, QINGYI · 2009 to 2013
$3.0M
Predictors of HPV16 Status and Outcomes of Oropharyngeal Cancer PatientsK07CA133099 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, GUOJUN · 2008 to 2012
$680k
Use of Serum HPV16 DNA as a Marker for Oropharyngeal Cancer RecurrenceR03CA128110 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI STURGIS, ERICH MADISON · 2007 to 2008
$154k
Cytokine Variants as Predictors of HPV-16 Status & Outcome of Oropharyngeal CanceR03CA135679 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, GUOJUN · 2008 to 2009
$154k
NCI NIH HHS CA016672NCI NIH HHS K07 CA133099NCI NIH HHS K07CA133099NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA131274NCI NIH HHS R01CA131274NCI NIH HHS R03 CA128110NCI NIH HHS R03CA128110NCI NIH HHS R03 CA135679NCI NIH HHS R03CA135679NIEHS NIH HHS R01 ES011740NIEHS NIH HHS R01ES011740
6 · The paper itself

Abstract

The unique effects of neighborhood-level economic deprivation on survival, recurrence, and second primary malignancy development were examined using adjusted Cox proportional hazards regression models among 1151 incident squamous cell carcinomas of the head and neck patients. Cancer site was examined as a potential moderator. Main analyses yielded null results; however, interaction analyses indicated poorer overall survival [HR=1.59 (1.00-2.53)] and greater second primary malignancy development [HR=2.99 (1.46-6.11)] among oropharyngeal cancer patients from highly deprived neighborhoods relative to less deprived neighborhoods. Results suggest a dual focus on individual and neighborhood risk factors could help improve clinical outcomes among oropharyngeal cancer patients.

Indexed as

Residence CharacteristicsAgedEpidemiologic StudiesFemaleHead and Neck NeoplasmsHealth Status DisparitiesHumansMaleMiddle AgedNeoplasms, Second PrimaryOutcome Assessment, Health CarePovertyProportional Hazards ModelsRetrospective StudiesRisk FactorsSocial Class

Identifiers

PMID22445028
PMCPMC3372668

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.