Evidence map›Paper›PMID 22444627›Full record

ArticleImmunity2012

B cells, not just for antibody anymore.

Kamal M Khanna, Leo Lefrançois

Open access · bronzeAbstract readComment
In one paragraph

Article in Immunity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Tumor necrosis factor superfamily in innate immunity and inflammation.Cold Spring Harbor perspectives in biology · 2014
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kamal M KhannaDepartment of Immunology, Center for Integrated Immunology and Vaccine Research, UCONN Health Center, Farmington, CT 06030, USA.
Leo Lefrançois
UConn Health · US

Funding

CD8 T CELL ACTIVATION AND MIGRATION IN VIVOR01AI041576 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI KHANNA, KAMAL MOHAN · 1997 to 2016
$5.3M
T Cell Response to Listeria Monocytogenes InfectionR01AI076457 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SHERIDAN, BRIAN S · 2009 to 2019
$3.8M
NIAID NIH HHS R01 AI041576NIAID NIH HHS R01 AI076457
6 · The paper itself

Abstract

B cell antibody production is thought to be crucial for protection against virus infection. In this issue of Immunity, Moseman et al. (2012) illustrate an antibody-independent role for B cells in macrophage activation that prevents virus dissemination after subcutaneous infection.

Identifiers

PMID22444627
PMCPMC3687144
OpenAlexW1992521665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.