ArticleScientific reports2012
Parasite-insecticide interactions: a case study of Nosema ceranae and fipronil synergy on honeybee.
Article in Scientific reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 212 citations in OpenAlex.
- Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence.Parasitology · 2024Pooled it
- Quantifying synergistic interactions: a meta-analysis of joint effects of chemical and parasitic stressors.Scientific reports · 2023Pooled it
- Disruption of Antioxidant Defense Systems in Honey Bees and Wild Bees Under Environmental Xenobiotic Pressure.Antioxidants (Basel, Switzerland) · 2026Review
- Review
- Cumulative Soil Metal Contamination Reshapes Oxidative and Neuroenzymatic Stress Responses in Ants Across an Industrial Pollution Gradient.Life (Basel, Switzerland) · 2026Article
- What's in a pollen provision? Using larval provisions to quantify pesticide exposure in Megachile rotundata (Hymenoptera: Megachilidae).Environmental entomology · 2026Article
- Review
- Neonicotinoids and Varroa mites force the extending of longevity in a bee colony during overwintering to forget.Scientific reports · 2025Article
- Synergistic Effects of Amitraz and Dinotefuran on Honey Bee Health: Impacts on Survival, Gene Expression, and Hypopharyngeal Gland Morphology.International journal of molecular sciences · 2025Article
- Environmental pollution effect on honey bees and their derived products: a comprehensive analysis.Environmental science and pollution research international · 2025Review
- The Role of Pathogens in Bumblebee Decline: A Review.Pathogens (Basel, Switzerland) · 2025Review
- Molecular Impact of Sublethal Spinetoram Exposure on Honeybee (International journal of molecular sciences · 2024Article
- Exploring the interactions between Nosema ceranae infection and the honey bee gut microbiome.Scientific reports · 2024Article
- Detrimental effects of amitraz exposure in honey bees (Apis mellifera) infected with Nosema ceranae.Parasitology research · 2024Article
- Beneficial Bacteria and Plant Extracts Promote Honey Bee Health and Reduce Nosema ceranae Infection.Probiotics and antimicrobial proteins · 2024Article
- Effects of Plant-Based Supplement on Oxidative Stress of Honey Bees (Animals : an open access journal from MDPI · 2023Article
- A GABA Receptor Modulator and Semiochemical Compounds Evidenced Using Volatolomics as Candidate Markers of Chronic Exposure to Fipronil inMetabolites · 2023Article
- Overlapping exposure effects of pathogen and dimethoate on honeybee (Frontiers in physiology · 2023Article
- Epidemiology of the MicrosporidiumInsects · 2022Article
- Effect of amide protoporphyrin derivatives on immune response in Apis mellifera.Scientific reports · 2022Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In ecosystems, a variety of biological, chemical and physical stressors may act in combination to induce illness in populations of living organisms. While recent surveys reported that parasite-insecticide interactions can synergistically and negatively affect honeybee survival, the importance of sequence in exposure to stressors has hardly received any attention. In this work, Western honeybees (Apis mellifera) were sequentially or simultaneously infected by the microsporidian parasite Nosema ceranae and chronically exposed to a sublethal dose of the insecticide fipronil, respectively chosen as biological and chemical stressors. Interestingly, every combination tested led to a synergistic effect on honeybee survival, with the most significant impacts when stressors were applied at the emergence of honeybees. Our study presents significant outcomes on beekeeping management but also points out the potential risks incurred by any living organism frequently exposed to both pathogens and insecticides in their habitat.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.