ArticleJournal of experimental botany2012
The BnGRF2 gene (GRF2-like gene from Brassica napus) enhances seed oil production through regulating cell number and plant photosynthesis.
Article in Journal of experimental botany, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 167 citations in OpenAlex.
- Mechanisms and Advances in Plant Lipid Regulatory Responses Under Biotic and Abiotic Stress.Genes · 2026Review
- The E3 ubiquitin ligase RHB1A and the transcription factor GRF1 form a regulatory module that orchestrates the trade-off between photosynthetic growth and salt tolerance in poplar.Plant communications · 2026Article
- Genome-Wide Identification and Characterization of Growth Regulatory Factor Gene Family inPlants (Basel, Switzerland) · 2025Article
- BnaC04.bZIP16 can be phosphorylated and inhibited by BnaA06.SnRK2 and negatively regulates the accumulation of fatty acids in Brassica napus.The Plant journal : for cell and molecular biology · 2025Article
- Plant oil biosynthesis and genetic improvement: progress, challenges, and opportunities.Plant physiology · 2025Review
- A chaperonin BnaC01.CCT8 contributes to silique length and seed weight by affecting auxin and jasmonic acid signalling in Brassica napus.Plant biotechnology journal · 2025Article
- Identification and characterization of the miR396f-GRF10 module in phase transition of Lilium.Planta · 2025Article
- Enhanced seed oil content by overexpressing LPAAT and WRI1 genes in tobacco plant.Plant cell reports · 2025Article
- In silico genome-wide analysis of the growth-regulating factor gene family and their expression profiling in Vitis vinifera under biotic stress.Cell biochemistry and biophysics · 2025Article
- Identification and functional analysis of growth- regulating factors involved in abiotic stress response inFrontiers in plant science · 2025Article
- Potential Roles of the GRF Transcription Factors in Sorghum Internodes during Post-Reproductive Stages.Plants (Basel, Switzerland) · 2024Article
- Genome-wide identification and expression profiling of growth‑regulating factor (GRF) and GRF‑interacting factor (GIF) gene families in chickpea and pigeonpea.Scientific reports · 2024Article
- Genome-wide identification and expression pattern analysis of the GRF transcription factor family in Astragalus mongholicus.Molecular biology reports · 2024Article
- Differential Response of MYB Transcription Factor Gene Transcripts to Circadian Rhythm in Tea Plants (International journal of molecular sciences · 2024Article
- Molecular mechanism of salinity and waterlogging tolerance in mangroveFrontiers in plant science · 2024Article
- Genome-wide characterization of the GRF transcription factors in potato (Frontiers in plant science · 2024Article
- Genome-Wide Analysis of Flax (International journal of molecular sciences · 2023Article
- Lipid Metabolism and Improvement in Oilseed Crops: Recent Advances in Multi-Omics Studies.Metabolites · 2023Review
- The SOD7/DPA4-GIF1 module coordinates organ growth and iron uptake in Arabidopsis.Nature plants · 2023Article
- Comparatively Evolution and Expression Analysis of GRF Transcription Factor Genes in Seven Plant Species.Plants (Basel, Switzerland) · 2023Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seed yield and oil content are two important agricultural characteristics in oil crop breeding, and a lot of functional gene research is being concentrated on increasing these factors. In this study, by differential gene expression analyses between rapeseed lines (zy036 and 51070) which exhibit different levels of seed oil production, BnGRF2 (Brassica napus growth-regulating factor 2-like gene) was identified in the high oil-producing line zy036. To elucidate the possible roles of BnGRF2 in seed oil production, the cDNA sequences of the rapeseed GRF2 gene were isolated. The Blastn result showed that rapeseed contained BnGRF2a/2b which were located in the A genome (A1 and A3) and C genome (C1 and C6), respectively, and the dominantly expressed gene BnGRF2a was chosen for transgenic research. Analysis of 35S-BnGRF2a transgenic Arabidopsis showed that overexpressed BnGRF2a resulted in an increase in seed oil production of >50%. Moreover, BnGRF2a also induced a >20% enlargement in extended leaves and >40% improvement in photosynthetic efficiency because of an increase in the chlorophyll content. Furthermore, transcriptome analyses indicated that some genes associated with cell proliferation, photosynthesis, and oil synthesis were up-regulated, which revealed that cell number and plant photosynthesis contributed to the increased seed weight and oil content. Because of less efficient self-fertilization induced by the longer pistil in the 35S-BnGRF2a transgenic line, Napin-BnGRF2a transgenic lines were further used to identify the function of BnGRF2, and the results showed that seed oil production also could increase >40% compared with the wild-type control. The results suggest that improvement to economically important characteristics in oil crops may be achieved by manipulation of the GRF2 expression level.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.