ArticleJournal of clinical microbiology2012
Molecular detection of Capillaria aerophila, an agent of canine and feline pulmonary capillariosis.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Lungworm disease in cats: ABCD guidelines on prevention and management.Journal of feline medicine and surgery · 2015Guideline
- Efficacy and safety of imidacloprid 10%/moxidectin 1% spot-on formulation in the treatment of feline infection by Capillaria aerophila.Parasitology research · 2012Trial
- Prevalence of Pulmonary Nematodes in Cats and Lung Ultrasound Findings in Separate Animal Cohorts: A Coprological, Molecular and Clinical Study.Animals : an open access journal from MDPI · 2026Article
- Endoparasites of European hedgehogs (Erinaceus europaeus) in Germany and their zoonotic potential: proposed Capillaria ovoreticulata genetically identified as Capillaria putorii.Parasites & vectors · 2025Article
- Integrated Taxonomic Approaches to Gastrointestinal and Urinary Capillariid Nematodes from Wild and Domestic Mammals.Pathogens (Basel, Switzerland) · 2025Article
- Eucoleus aerophilus (syn. Capillaria aerophila) infection in zoo-housed arctic foxes (Vulpes lagopus).Acta parasitologica · 2025Article
- Prevalence and genetic diversity of the lung nematode Eucoleus aerophilus in red foxes (Vulpes vulpes) in Central Europe (Poland) assessed by PCR and flotation.Scientific reports · 2024Article
- Human parasitic infections of the class Adenophorea: global epidemiology, pathogenesis, prevention and control.Infectious diseases of poverty · 2024Review
- Helminth diversity and seasonality of Angiostrongylus cantonensis in hedgehogs from Mallorca.Parasite (Paris, France) · 2024Article
- Lungworms of Non-Ruminant Terrestrial Mammals and Humans in Iran.Pathogens (Basel, Switzerland) · 2023Review
- First report ofInternational journal for parasitology. Parasites and wildlife · 2023Article
- Wild Mesocarnivores as Reservoirs of Endoparasites Causing Important Zoonoses and Emerging Bridging Infections across Europe.Pathogens (Basel, Switzerland) · 2023Review
- Cardio-pulmonary parasites of the European wildcat (Felis silvestris) in Germany.Parasites & vectors · 2022Article
- Cardiorespiratory nematodes and co-infections with gastrointestinal parasites in new arrivals at dog and cat shelters in north-western Spain.Transboundary and emerging diseases · 2022Article
- Canine and Feline Parasitology: Analogies, Differences, and Relevance for Human Health.Clinical microbiology reviews · 2021Review
- Efficacy of milbemycin oxime/afoxolaner chewable tablets (NEXGARD SPECTRAParasites & vectors · 2021Article
- An Unusual Case of Mixed Respiratory Capillariosis in a Dog.Pathogens (Basel, Switzerland) · 2021Article
- What the fox? CrypticCurrent research in parasitology & vector-borne diseases · 2021Article
- Clinical-parasitological Screening for Respiratory Capillariosis in Cats in Urban Environments.Helminthologia · 2020Article
- Ventral dermatitis in rowi (International journal for parasitology. Parasites and wildlife · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Capillaria aerophila, a trichuroid nematode causing pulmonary infections in wild and domestic carnivores, is occasionally and potentially poorly recognized in infections of humans due to clinicopathological mimicry and a lack of accurate, robust laboratory diagnostics. The present work evaluated the efficiency of a DNA-based assay amplifying a partial cytochrome c oxidase subunit 1 (cox1) gene of C. aerophila in the diagnosis of lung capillariosis. Fecal samples from 34 dogs and 10 cats positive at parasitological examination for C. aerophila and other endoparasites (i.e., other lungworms, whipworms, roundworms, hookworms, tapeworms, and/or coccidia) and from 44 animals negative for C. aerophila but positive for other endoparasites were molecularly examined. Of the 44 samples positive for C. aerophila at copromicroscopy, 43 scored positive (i.e., 33/34 dogs and 10/10 cats) in seminested PCR, resulting in a sensitivity of 97 to 100%. Samples that were copromicroscopy negative for C. aerophila although positive for other endoparasites never produced a PCR product or nonspecific amplicons. The specific PCR amplification of C. aerophila (i.e., specificity of 100%) was confirmed by a nucleotide sequence analysis of the cox1 amplicons. The potential implications of the molecular diagnosis of lung capillariosis are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.