Evidence map›Paper›PMID 22442295›Full record

ReviewDiabetes2012

The clinical potential of C-peptide replacement in type 1 diabetes.

John Wahren, Asa Kallas, Anders A F Sima

Open access · bronzeAbstract readReview
In one paragraph

Review in Diabetes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Pooled it
  2. Influence of food patterns on endothelial biomarkers: a systematic review.Journal of clinical hypertension (Greenwich, Conn.) · 2014
    Pooled it
  3. Trial
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  8. Review
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  16. Article
  17. Biological activity versus physiological function of proinsulin C-peptide.Cellular and molecular life sciences : CMLS · 2021
    Article
  18. Lentivirus Mediated Pancreatic Beta-Cell-Specific Insulin Gene Therapy for STZ-Induced Diabetes.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  19. C-peptide and residual β-cell function in pediatric diabetes - state of the art.Pediatric endocrinology, diabetes, and metabolism · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

John WahrenDepartment of Molecular Medicine and Surgery, Karolinska Institutet,Stockholm, Sweden. john.wahren@ki.se
Asa Kallas
Anders A F Sima
Karolinska Institutet · SEDetroit Medical Center · US

Funding

NIDDK NIH HHS R01-DK-081470-01PHS HHS NIH-NIDDK-05-05
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsC-PeptideDiabetes ComplicationsDiabetes Mellitus, Type 1HumansInsulin-Secreting CellsProtein BindingC-Peptide

Identifiers

PMID22442295
PMCPMC3314360
OpenAlexW2143255381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.