ReviewHeart (British Cardiac Society)2012
Pathogenesis and diagnosis of myocarditis.
Review in Heart (British Cardiac Society), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 137 citations in OpenAlex.
- Prevalence of neutralizing autoantibodies against type I interferon in dengue patients.Journal of human immunity · 2026Article
- Outcomes by cardiovascular magnetic resonance in patients with clinically suspected myocardial inflammation.The international journal of cardiovascular imaging · 2026Article
- Global lifetime risk of developing myocarditis, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021.BMJ open · 2026Article
- An Unexpected Complication of Gastroenteritis.Cureus · 2025Article
- A comparative review of myocarditis in pediatrics versus adults: pathogenesis, diagnosis, and management.Frontiers in immunology · 2025Review
- Characteristics of Electrocardiogram Findings in Fulminant Myocarditis.Journal of cardiovascular development and disease · 2023Article
- Acute myocarditis in a young male after gastroenteritis: A case report and literature review.Clinical case reports · 2022Article
- Article
- Neurological Manifestations of Myocarditis.Current neurology and neuroscience reports · 2022Review
- From Streptococcal Pharyngitis/Tonsillitis to Myocarditis: A Systematic Review.Journal of cardiovascular development and disease · 2022Review
- Construction of Immune-Related ceRNA Network in Dilated Cardiomyopathy: Based on Sex Differences.Frontiers in genetics · 2022Article
- PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism.Frontiers in pharmacology · 2022Review
- A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor-Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention.Cancer discovery · 2021Article
- Programmed Death-Ligand 2 Deficiency Exacerbates Experimental Autoimmune Myocarditis in Mice.International journal of molecular sciences · 2021Article
- Resident cardiac macrophages: crucial modulators of cardiac (patho)physiology.Basic research in cardiology · 2020Review
- Rethinking COVID-19 in children: Lessons learned from pediatric viral and inflammatory cardiovascular diseases.Progress in pediatric cardiology · 2020Article
- Diagnostic and prognostic role of electrocardiogram in acute myocarditis: A comprehensive review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020Review
- Sex differences in inflammation, redox biology, mitochondria and autoimmunity.Redox biology · 2020Review
- Article
- Cardiac MRI Evaluation of Myocarditis.Current treatment options in cardiovascular medicine · 2019Review
Corrections and comments
- Reprinted as
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Acute myocarditis is an inflammatory disease of the heart muscle that may progress to dilated cardiomyopathy and chronic heart failure. A number of factors including the sex hormone testosterone, components of innate immunity, and profibrotic cytokines have been identified in animal models as important pathogenic mechanisms that increase inflammation and susceptibility to chronic dilated cardiomyopathy. The clinical presentation of acute myocarditis is non-specific and mimics more common causes of heart failure and arrhythmias. Suspected myocarditis is currently confirmed using advanced non-invasive imaging and histopathologic examination of heart tissue. However, the diverse presentations of myocarditis and the lack of widely available, safe, and accurate non-invasive diagnostic tests remain major obstacles to early diagnosis and population based research. Recent advances in the understanding of disease pathogenesis described in this review should lead to more accurate diagnostic algorithms and non-invasive tests.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.