ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
fMRI repetition suppression for familiar but not arbitrary actions with tools.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 79 citations in OpenAlex.
- Organization of affordance processing in perception-action systems.Frontiers in human neuroscience · 2026Article
- Object representations in human ventral and dorsal cortex depend on display format and physical distance.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Attenuation of High Gamma Activity by Repetitive Motor Tasks.Human brain mapping · 2025Article
- Internal representations of the canonical real-world distance of objects.Journal of vision · 2024Article
- Human Neuroimaging Reveals Differences in Activation and Connectivity between Real and Pantomimed Tool Use.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Variational relevance evaluation of individual fMRI data enables deconstruction of task-dependent neural dynamics.Communications biology · 2023Article
- Investigating the effects of the aging brain on real tool use performance-an fMRI study.Frontiers in aging neuroscience · 2023Article
- The parietal lobe evolution and the emergence of material culture in the human genus.Brain structure & function · 2023Review
- Action goals and the praxis network: an fMRI study.Brain structure & function · 2022Article
- The role of the anterior temporal cortex in action: evidence from fMRI multivariate searchlight analysis during real object grasping.Scientific reports · 2022Article
- Domain-specific connectivity drives the organization of object knowledge in the brain.Handbook of clinical neurology · 2022Review
- Neural encoding and functional interactions underlying pantomimed movements.Brain structure & function · 2021Article
- Hand-Selective Visual Regions Represent How to Grasp 3D Tools: Brain Decoding during Real Actions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Distinct auditory and visual tool regions with multisensory response properties in human parietal cortex.Progress in neurobiology · 2020Article
- Article
- Article
- Language as a Tool: Motor Proficiency Using a Tool Predicts Individual Linguistic Abilities.Frontiers in psychology · 2019Article
- Concurrent Cortical Representations of Function- and Size-Related Object Affordances: An fMRI Study.Cognitive, affective & behavioral neuroscience · 2018Article
- Fronto-parietal coding of goal-directed actions performed by artificial agents.Human brain mapping · 2018Article
- Functional versus effector-specific organization of the human posterior parietal cortex: revisited.Journal of neurophysiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
For humans, daily life is characterized by routine interaction with many different tools for which corresponding actions are specified and performed according to well-learned procedures. The current study used functional MRI (fMRI) repetition suppression (RS) to identify brain areas underlying the transformation of visually defined tool properties to corresponding motor programs for conventional use. Before grasping and demonstrating how to use a specific tool, participants passively viewed either the same (repeated) tool or a different (non-repeated) tool. Repetition of tools led to reduced fMRI signals (RS) within a selective network of parietal and premotor areas. Comparison with newly learned, arbitrarily defined control actions revealed specificity of RS for tool use, thought to reflect differences in the extent of previous sensorimotor experience. The findings indicate that familiar tools are visually represented within the same sensorimotor areas underlying their dexterous use according to learned properties defined by previous experience. This interpretation resonates with the broader concept of affordance specification considered fundamental to action planning and execution whereby action-relevant object properties (affordances) are visually represented in sensorimotor areas. The current findings extend this view to reveal that affordance specification in humans includes learned object properties defined by previous sensorimotor experience. From an evolutionary perspective, the neural mechanisms identified in the current study offer clear survival advantage, providing fast efficient transformation of visual information to appropriate motor responses based on previous experience.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.