ArticleEuropean archives of psychiatry and clinical neuroscience2012
A comparison of adolescent- and adult-onset first-episode, non-affective psychosis: 2-year follow-up.
Article in European archives of psychiatry and clinical neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Rate and predictors of remission and recovery in first-episode psychosis: A 12-year follow-up of randomized-controlled trial on early intervention.Molecular psychiatry · 2026Trial
- A comparative analysis of age of onset and associated factors in non-refugee immigrants versus native-born individuals with psychotic disorders.European journal of psychotraumatology · 2025Article
- Treatment Outcomes for Asian Americans Diagnosed with Schizophrenia Spectrum Disorder.Community mental health journal · 2025Article
- Depressive symptoms and their relationship with negative and other psychotic symptoms in early onset psychosis.European child & adolescent psychiatry · 2021Article
- Differences in the regulation of inflammatory pathways in adolescent- and adult-onset first-episode psychosis.European child & adolescent psychiatry · 2019Article
- Article
- Posttraumatic growth following a first episode of psychosis: a mixed methods research protocol using a convergent design.BMC psychiatry · 2016Article
- Facial emotional expression in schizophrenia adolescents during verbal interaction with a parent.European archives of psychiatry and clinical neuroscience · 2013Article
- Schizophrenia: from risk genes to outcome and comorbidity.European archives of psychiatry and clinical neuroscience · 2012Article
- Early detection and intervention of psychosis in children and adolescents: urgent need for studies.European child & adolescent psychiatry · 2012Article
- Family History of Psychiatric Disorders and Clinical Factors Associated With a Schizophrenia Diagnosis.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
This study aimed to compare 2-year outcome among individuals with early-onset (EO; <18 years) versus adult-onset (AO) first-episode, non-affective psychosis. We compared clinical and treatment characteristics of 43 EO and 189 AO patients 2 years after their inclusion in a clinical epidemiologic population-based cohort study of first-episode psychosis. Outcome variables included symptom severity, remission status, drug abuse, treatment utilization, cognition and social functioning. At baseline, EO patients were more symptomatically compromised. However, these initial baseline differences were no longer significant at the 2-year follow-up. This study challenges the findings of a larger and older literature base consisting primarily of non-comparative studies concluding that teenage onset indicates a poor outcome. Our results indicate that adolescent-onset and adult-onset psychosis have similar prognostic trajectories, although both may predict a qualitatively different course from childhood-onset psychosis.
Indexed as
Identifiers
22441715What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.