Evidence map›Paper›PMID 22441550›Full record

ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2012

[Spontaneous change of malignancy of solid malignant tumors : statistical investigations of colorectal and pancreatic carcinoma].

F Stelzner

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Nitric oxide represses the proliferation of Caco-2 cells by inducing S-GInternational journal of physiology, pathophysiology and pharmacology · 2019
    Article
  3. [Surgery without anatomy?].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016
    Review
  4. Article
  5. [Prediction of prognosis of pancreatic cancer based on the homing area].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

F StelznerChirurgische Universitätsklinik Bonn, Deutschland. Stel33345@aol.com
Chirurgische Universitätsklinik Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distribution curves of grades of malignancy for colorectal carcinomas and pancreatic carcinomas have not been stable over the years and investigations have shown a clear variability in the temporal distribution. Colon carcinomas were found to diminish considerably in aggressiveness in different time periods and colorectal carcinomas were found to increase in aggressiveness in some years. However, the distribution curve of grades of malignancy varies in both carcinomas over time and this variation follows a random distribution. In contrast to colorectal carcinomas, pancreatic carcinomas have not been followed up for very long time periods. While the distribution curve of malignancy was unchanged in most countries an increase in malignancy was observed in two countries. For colorectal and pancreatic carcinomas increases in malignancy are linked to a highly significant decrease in the number of cancers with lowest grades of malignancy. Even though the exact nature of variations in these malignancy distribution curves is incompletely understood, these variations appear important for comparative outcome statistics in cancer therapy as the aggressiveness of these malignancies has a direct bearing on the overall prognosis.

Indexed as

Disease ProgressionCell ProliferationCell Transformation, NeoplasticColonColorectal NeoplasmsCross-Cultural ComparisonDisease-Free SurvivalFollow-Up StudiesHumansNeoplasm GradingNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasms, Multiple PrimaryNeoplasm StagingOutcome Assessment, Health CarePancreas

Identifiers

PMID22441550
OpenAlexW998894443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.