Trial reportJournal of perinatology : official journal of the California Perinatal Association2013
Probiotics supplementation increases intestinal blood flow velocity in extremely low birth weight preterm infants.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 7 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Pooled it
- Effect of probiotics on necrotizing enterocolitis in preterm infants: a network meta-analysis of randomized controlled trials.BMC pediatrics · 2025Pooled it
- Lactobacillus rhamnosus GG as a probiotic for preterm infants: a strain specific systematic review and meta-analysis.European journal of clinical nutrition · 2024Pooled it
- Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants.The Cochrane database of systematic reviews · 2023Pooled it
- Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants.The Cochrane database of systematic reviews · 2020Pooled it
- Effects of Probiotics on Necrotizing Enterocolitis, Sepsis, Intraventricular Hemorrhage, Mortality, Length of Hospital Stay, and Weight Gain in Very Preterm Infants: A Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2017Pooled it
- Probiotics and Time to Achieve Full Enteral Feeding in Human Milk-Fed and Formula-Fed Preterm Infants: Systematic Review and Meta-Analysis.Nutrients · 2016Pooled it
- Probiotics to prevent necrotizing enterocolitis in very low birth weight infants: A network meta-analysis.Frontiers in pediatrics · 2023Review
- Early gut microbiota in very low and extremely low birth weight preterm infants with feeding intolerance: a prospective case-control study.Journal of microbiology (Seoul, Korea) · 2022Observational
- Gastro-oesophageal reflux: a mixed methods study of infants admitted to hospital in the first 12 months following birth in NSW (2000-2011).BMC pediatrics · 2018Article
- [Research progress of the application of probiotics in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016Review
- Probiotics and necrotizing enterocolitis: finding the missing pieces of the probiotic puzzle.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine whether probiotics supplementation affects intestinal blood flow velocity in extremely low birth weight neonates. STUDY
designIn this randomized, double-blind, placebo-controlled study, probiotics were added to the first enteral feeding and continued until discharge or 34 weeks postmenstrual age. Pulsed Doppler was used to measure preprandial and postprandial (at 30 and 60 min) time-averaged mean velocity (TAMV), peak systolic velocity (PSV) and end diastolic velocity (EDV) during the second week of life after ≥ 7 days of probiotics supplementation.
resultA total of 31 infants were studied, 15 were randomized to the probiotic and 16 to the placebo groups. There was a significant postprandial increase in TAMV for the probiotic vs the placebo group (P=0.035), with PSV and EDV showing a trend. Demographic and clinical variables were similar between the groups.
conclusionProbiotics administration significantly increases postprandial intestinal blood flow in extremely low birth weight preterm neonates when compared with the placebo group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.