ReviewCurrent opinion in virology2012
Targeted entry of enveloped viruses: measles and herpes simplex virus I.
Review in Current opinion in virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Cell-Int: a cell-cell interaction assay to identify native membrane protein interactions.Life science alliance · 2024Article
- Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells.Sub-cellular biochemistry · 2024Review
- Tailoring Uptake Efficacy of HSV-1 gD Derived Carrier Peptides.Biomolecules · 2020Article
- Oncolytic Measles Virotherapy and Opposition to Measles Vaccination.Mayo Clinic proceedings · 2019Review
- Oncogenes: The Passport for Viral Oncolysis Through PKR Inhibition.Biomarkers in cancer · 2016Review
- Cancer targeted therapeutics: From molecules to drug delivery vehicles.Journal of controlled release : official journal of the Controlled Release Society · 2015Article
- MicroRNA-mediated multi-tissue detargeting of oncolytic measles virus.Cancer gene therapy · 2014Article
- The measles virus hemagglutinin stalk: structures and functions of the central fusion activation and membrane-proximal segments.Journal of virology · 2014Article
- Structural basis of efficient contagion: measles variations on a theme by parainfluenza viruses.Current opinion in virology · 2014Review
- Glioma virus therapies between bench and bedside.Neuro-oncology · 2014Review
- New viruses for cancer therapy: meeting clinical needs.Nature reviews. Microbiology · 2014Review
- Hydrophobic and charged residues in the central segment of the measles virus hemagglutinin stalk mediate transmission of the fusion-triggering signal.Journal of virology · 2013Article
- Virus-receptor interactions and receptor-mediated virus entry into host cells.Sub-cellular biochemistry · 2013Review
- Membrane fusion triggering: three modules with different structure and function in the upper half of the measles virus attachment protein stalk.The Journal of biological chemistry · 2012Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
We compare the receptor-based mechanisms that a small RNA virus and a larger DNA virus have evolved to drive the fusion of viral and cellular membranes. Both systems rely on tight control over triggering the concerted refolding of a trimeric fusion protein. While measles virus entry depends on a receptor-binding protein and a fusion protein only, the herpes simplex virus (HSV) is more complex and requires four viral proteins. Nevertheless, in both viruses a receptor-binding protein is required for triggering the membrane fusion process. Moreover, specificity domains can be appended to these receptor-binding proteins to target virus entry to cells expressing a designated receptor. We discuss how principles established with measles and HSV can be applied to targeting other enveloped viruses, and alternatively how retargeted envelopes can be fitted on foreign capsids.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.