ReviewBiological psychiatry2012
Shining light on wakefulness and arousal.
Review in Biological psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Divergent effects of oxytocin on "mind-reading" in healthy males.Cognitive, affective & behavioral neuroscience · 2022Trial
- Changes in brain arousal (EEG-vigilance) after therapeutic sleep deprivation in depressive patients and healthy controls.Scientific reports · 2018Trial
- Trial
- Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Systematic review and meta-analysis of early visual processing, social cognition, and functional outcomes in schizophrenia spectrum disorders.Schizophrenia research. Cognition · 2025Review
- Strategic stabilization of arousal boosts sustained attention.Current biology : CB · 2024Article
- The Gaze of Schizophrenia Patients Captured by Bottom-up Saliency.Schizophrenia (Heidelberg, Germany) · 2024Article
- Detection of dynamic changes of electrodermal activity to predict the classroom performance of college students.Cognitive neurodynamics · 2024Article
- FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system.Cell metabolism · 2023Article
- Associations between comorbid anxiety and sleep disturbance in people with bipolar disorder: Findings from actigraphy and subjective sleep measures.Journal of affective disorders · 2022Article
- Early-stage visual perception impairment in schizophrenia, bottom-up and back again.Schizophrenia (Heidelberg, Germany) · 2022Review
- Sleep Disturbances and Their Association With Quality of Life in Older Psychiatric Patients During the COVID-19 Pandemic.Journal of geriatric psychiatry and neurology · 2022Article
- Network Analysis of Depression, Anxiety, Posttraumatic Stress Symptoms, Insomnia, Pain, and Fatigue in Clinically Stable Older Patients With Psychiatric Disorders During the COVID-19 Outbreak.Journal of geriatric psychiatry and neurology · 2022Article
- Exploring what synchronized physiological arousal can reveal about the social regulatory process in a collaborative argumentation activity.Frontiers in psychology · 2022Article
- Insomnia and Related Factors During the Delta Wave of the COVID-19 Pandemic in the Kingdom of Bahrain: A Cross-Sectional Study.Nature and science of sleep · 2022Article
- The prevalence of depressive and anxiety symptoms and their associations with quality of life among clinically stable older patients with psychiatric disorders during the COVID-19 pandemic.Translational psychiatry · 2021Article
- Hyper-Reactivity to Salience Limits Social Interaction Among Infants Born Pre-term and Infant Siblings of Children With ASD.Frontiers in psychiatry · 2021Article
- Prepronociceptin-Expressing Neurons in the Extended Amygdala Encode and Promote Rapid Arousal Responses to Motivationally Salient Stimuli.Cell reports · 2020Article
- Perceptual Behavior Depends Differently on Pupil-Linked Arousal and Heartbeat Dynamics-Linked Arousal in Rats Performing Tactile Discrimination Tasks.Frontiers in systems neuroscience · 2020Article
- Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents.Nature communications · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Alterations in arousal states are associated with multiple neuropsychiatric disorders, including generalized anxiety disorders, addiction, schizophrenia, and depression. Therefore, elucidating the neurobiological mechanisms controlling the boundaries between arousal, hyperarousal, and hypoarousal is a crucial endeavor in biological psychiatry. Substantial research over several decades has identified distinct arousal-promoting neural populations in the brain; however, how these nuclei act individually and collectively to promote and maintain wakefulness and various arousal states is unknown. We have recently applied optogenetic technology to the repertoire of techniques used to study arousal. Here, we discuss the recent results of these experiments and propose future use of this approach as a way to understand the complex dynamics of neural circuits controlling arousal and arousal-related behaviors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.