ArticleJournal of prenatal medicine2011
Antiphospholipid Syndrome during pregnancy: the state of the art.
Article in Journal of prenatal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- The Impact of Autoantibodies on IVF Treatment and Outcome: A Systematic Review.International journal of molecular sciences · 2019Pooled it
- Association between pregnancy outcomes prior to diagnosis and clinical characteristics following diagnosis in patients with systemic sclerosis.Clinical rheumatology · 2026Article
- Life-Saving Intracranial Mechanical Thrombectomy for Acute Ischemic Stroke in Pregnancy: Balancing Maternal and Fetal Risk.Journal of medical cases · 2026Article
- Effects of hydroxychloroquine sulfate combined with aspirin and enoxaparin sodium therapy on perinatal outcomes in patients with undifferentiated connective tissue disease-related recurrent miscarriage: a retrospective clinical study.BMC pregnancy and childbirth · 2026Article
- Invasive pituitary carcinoma associated with antiphospholipid syndrome: a rare case revealed by postpartum cerebral venous thrombosis (case report).The Pan African medical journal · 2026Article
- The role of neutrophil extracellular traps in antiphospholipid syndrome.Frontiers in immunology · 2026Review
- Neutrophils at the Maternal-Fetal Interface: Agents of Protection or Destruction?American journal of reproductive immunology (New York, N.Y. : 1989) · 2025Review
- Article
- Even low levels of anticardiolipin antibodies are associated with pregnancy-related complications: A monocentric cohort study.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Antiphospholipid syndrome in pregnancy: a comprehensive literature review.BMC pregnancy and childbirth · 2025Review
- Exploring Biomarkers to Predict Thrombogenic Risk in Pregnancy.Journal of clinical medicine · 2025Article
- A case series on TNF-α inhibitors for APS- induced high-risk pregnancies.Journal of clinical and translational science · 2025Article
- Review
- Catastrophic antiphospholipid syndrome after pregnancy complicated by hemolysis, elevated liver enzymes and low platelets syndrome.Obstetric medicine · 2024Article
- A Retrospective Observational Study Using Administrative Databases to Assess the Risk of Spontaneous Abortions Related to Environmental and Socioeconomic Conditions.Life (Basel, Switzerland) · 2023Article
- Influence of Antiphospholipid Antibody-Associated Thrombophilia on the Risk of Preterm Birth: A Systematic Review.Journal of clinical medicine · 2023Review
- Laboratory Testing of Hemostasis in Pregnancy: A Brief Overview.Methods in molecular biology (Clifton, N.J.) · 2023Review
- Identification of Single Nucleotide Polymorphisms as Biomarkers for Recurrent Pregnancy Loss in Korean Women.Journal of Korean medical science · 2022Article
- Usefulness of low-dose combined spinal epidural anesthesia for a woman with systemic lupus erythematosus, mechanical prosthesis in the mitral valve position, and worsening heart failure presenting for cesarean delivery.Proceedings (Baylor University. Medical Center) · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstetric complications are the hallmark of antiphospholipid syndrome. Recurrent miscarriage, early delivery, oligohydramnios, prematurity, intrauterine growth restriction, fetal distress, fetal or neonatal thrombosis, pre-eclampsia/eclampsia, HELLP syndrome, arterial or venous thrombosis and placental insufficiency are the most severe APS-related complication for pregnant women. Antiphospholipid antibodies promote activation of endothelial cells, monocytes and platelets, causing an overproduction of tissue factor and thromboxane A2. Complement activation might have a central pathogenetic role. These factors, associated with the typical changes in the hemostatic system during normal pregnancy, result in a hypercoagulable state. This is responsible of thrombosis that is presumed to provoke many of the pregnancy complications associated with APS. Obstetric care is based on combined medical-obstetric high-risk management and treatment with the association between aspirin and heparin. This review aims to deter- mine the current state of the art of APS by investigating the knowledge achievements of recent years, to provide the most appropriate diagnostic and therapeutic management for pregnant women suffering from this syndrome.
Indexed as
Identifiers
22439075PMC3279165W1637992064What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.