Evidence map›Paper›PMID 22438553›Full record

ArticleJournal of virology2012

Virus-derived gene expression and RNA interference vector for grapevine.

Elizabeth G Kurth, Valera V Peremyslov, Alexey I Prokhnevsky, Kristin D Kasschau, Marilyn Miller, James C Carrington, Valerian V Dolja

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Horticulture research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. LtGAPR1 Is a Novel Secreted Effector fromJournal of fungi (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elizabeth G KurthDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, Oregon, USA.
Valera V Peremyslov
Alexey I Prokhnevsky
Kristin D Kasschau
Marilyn Miller
James C Carrington
Valerian V Dolja
Oregon State University · US

Funding

Genetic Analysis of RNA Virus-Host InteractionR37AI043288 · NIAID · OREGON STATE UNIVERSITY · PI CARRINGTON, JAMES C · 2008 to 2017
$3.1M
GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTIONR01AI043288 · NIAID · WASHINGTON STATE UNIVERSITY · PI CARRINGTON, JAMES C · 1998 to 2007
$1.7M
GENETIC ANALYSIS OF RNA VIRUS-HOST INTERACTIONR21AI043288 · NIAID · WASHINGTON STATE UNIVERSITY · PI CARRINGTON, JAMES C · 1997 to 1997
–
NIAID NIH HHS AI43288NIAID NIH HHS R01 AI043288NIAID NIH HHS R21 AI043288NIAID NIH HHS R37 AI043288
6 · The paper itself

Abstract

The improvement of the agricultural and wine-making qualities of the grapevine (Vitis vinifera) is hampered by adherence to traditional varieties, the recalcitrance of this plant to genetic modifications, and public resistance to genetically modified organism (GMO) technologies. To address these challenges, we developed an RNA virus-based vector for the introduction of desired traits into grapevine without heritable modifications to the genome. This vector expresses recombinant proteins in the phloem tissue that is involved in sugar transport throughout the plant, from leaves to roots to berries. Furthermore, the vector provides a powerful RNA interference (RNAi) capability of regulating the expression of endogenous genes via virus-induced gene-silencing (VIGS) technology. Additional advantages of this vector include superb genetic capacity and stability, as well as the swiftness of technology implementation. The most significant applications of the viral vector include functional genomics of the grapevine and disease control via RNAi-enabled vaccination against pathogens or invertebrate pests.

Indexed as

Gene ExpressionGenetic VectorsRNA InterferenceCarbohydrate MetabolismClosteroviridaeGene Expression RegulationMolecular Sequence DataPlant ProteinsSequence Analysis, DNAVitisPlant Proteins

Identifiers

PMID22438553
PMCPMC3372183
OpenAlexW2026574777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.