ArticleJournal of virology2012
Recombinant monoclonal antibody recognizes a unique epitope on varicella-zoster virus immediate-early 63 protein.
Article in Journal of virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphology.Journal of neurovirology · 2016Article
- Comprehensive analysis of varicella-zoster virus proteins using a new monoclonal antibody collection.Journal of virology · 2013Article
- In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles.Translational biomedicine · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
We previously constructed a recombinant monoclonal antibody (rec-MAb 63P4) that detects immediate-early protein IE63 encoded by varicella-zoster virus (VZV) in the cytoplasm of productively infected cells. Here, we used ORF63 truncation mutants to map the rec-MAb 63P4 binding epitope to amino acids 141 to 150 of VZV IE63, a region not shared with other widely used anti-IE63 antibodies, and found that the recombinant antibody does not bind to the simian IE63 counterpart.
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Registered trials
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