ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2012
New frontiers in cell competition.
Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 69 citations in OpenAlex.
- Basal Invasion of Cancer Cells Driven by Cell-Cell Interactions: An Affirmative Role of Cell Competition in Cancer Progression.Cancer science · 2025Review
- Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway.Nature communications · 2023Article
- Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila.PLoS genetics · 2022Article
- Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth.Nature communications · 2020Article
- Review
- Prostaglandin EGenes to cells : devoted to molecular & cellular mechanisms · 2020Article
- Signal transduction in the early Drosophila follicle stem cell lineage.Current opinion in insect science · 2020Review
- Regulation of the Hippo signaling pathway by deubiquitinating enzymes in cancer.Genes & diseases · 2019Review
- Cell Extrusion: A Stress-Responsive Force for Good or Evil in Epithelial Homeostasis.Developmental cell · 2018Review
- Mechanisms of cell competition emerging from Drosophila studies.Current opinion in cell biology · 2017Article
- Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts.Developmental cell · 2017Article
- Chronic activation of JNK JAK/STAT and oxidative stress signalling causes the loser cell status.Nature communications · 2017Article
- The SWI/SNF Complex Protein Snr1 Is a Tumor Suppressor inCancer research · 2017Article
- p53 pathway is involved in cell competition during mouse embryogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia.Developmental cell · 2016Article
- Whole-Genome Sequencing and iPLEX MassARRAY Genotyping Map an EMS-Induced Mutation Affecting Cell Competition in Drosophila melanogaster.G3 (Bethesda, Md.) · 2016Article
- Troponin-I enhances and is required for oncogenic overgrowth.Oncotarget · 2016Article
- MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status.Scientific reports · 2016Article
- Mechanical cell competition kills cells via induction of lethal p53 levels.Nature communications · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Cellular communication is at the heart of animal development, and guides the specification of cell fates, the movement of cells within and between tissues, and the coordinated arrangement of different body parts. During organ and tissue growth, cell-cell communication plays a critical role in decisions that determine whether cells survive to contribute to the organism. In this review, we discuss recent insights into cell competition, a social cellular phenomenon that selects the fittest cells in a tissue, and as such potentially contributes to the regulation of its growth and final size. The field of cell competition has seen a huge explosion in its study in the last several years, facilitated by the increasingly sophisticated genetic and molecular technology available in Drosophila and driven by its relevance to stem cell biology and human cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.