ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2013
Management and outcome of salivary duct carcinoma in major salivary glands.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Estimating survival after salvage surgery for recurrent salivary gland cancers: Systematic review.Head & neck · 2022Pooled it
- The implicated clinical factors for outcomes in 304 patients with salivary duct carcinoma: Multi-institutional retrospective analysis in Japan.Head & neck · 2022Article
- Solitary late spinal metastasis from apocrine salivary duct carcinoma: Case report.Surgical neurology international · 2021Article
- A population-based competing risk survival analysis of patients with salivary duct carcinoma.Annals of translational medicine · 2020Article
- Salivary Duct Carcinoma and Invasive Ductal Carcinoma of the Breast: A Comparative Immunohistochemical Study.Head and neck pathology · 2018Article
- Salivary duct carcinoma: An aggressive salivary gland malignancy with opportunities for targeted therapy.Oral oncology · 2017Review
- Salivary duct carcinoma treated with cetuximab-based targeted therapy: A case report.Molecular and clinical oncology · 2017Article
- A 20-Year Review of 75 Cases of Salivary Duct Carcinoma.JAMA otolaryngology-- head & neck surgery · 2016Article
- Salivary Duct Carcinoma of the Deep Lobe of the Parotid Gland: A Rare Clinical Finding.Archives of plastic surgery · 2016Article
- Early T Stage Salivary Duct Carcinoma: Outcomes and Implications for Patient Counseling.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2015Article
- Salivary duct carcinoma: A clinopathological report of 11 cases.Oncology letters · 2015Article
- Recent advances in the diagnostic pathology of salivary carcinomas.Virchows Archiv : an international journal of pathology · 2014Review
- Postoperative radiotherapy in patients with salivary duct carcinoma: clinical outcomes and prognostic factors.Journal of radiation research · 2013Article
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8 authors at 4 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Salivary duct carcinoma (SDC) is a rare and aggressive malignancy with poor prognosis. Its histomorphology is distinctly reminiscent of the ductal carcinoma of the breast. We reviewed the treatment and outcome of SDCs at a single tertiary care centre. Twenty-five cases of SDC of major salivary gland origin, diagnosed and treated at the Department of Otolaryngology, Head and Neck Surgery, Helsinki University Central Hospital, Helsinki, Finland, during a 14-year period from 1997 to 2011, were reviewed retrospectively. Survival outcome was analyzed for 18 patients with a minimum follow-up of 24 months. There were 16 male (64 %) and 9 female (36 %) patients with a median age of 61 years (range 36-82 years). The majority of the cases occurred in the parotid gland (n = 21, 84 %) followed by the submandibular gland (n = 4, 16 %). The primary treatment consisted of surgical resection in all cases and 17 (68 %) patients also underwent neck dissection. Most of the patients (n = 18, 72 %) were treated with postoperative radiotherapy. Seven patients (28 %) had a disease recurrence within a median follow-up time of 15 months (range 3-27 months). In the group (n = 18) with a minimum follow-up time of 24 months, the 2- and 5-year overall and disease-specific survival rates were 66, 41 % and 75, 55 %, respectively. These results confirm the aggressive nature of SDCs in major salivary glands. Diagnostics and management of these tumours need to be centralized in experienced surgical Head and Neck Oncology Centres, and new treatment strategies should be investigated.
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