ArticleBiology of sex differences2012
Sex differences in behavioral decision-making and the modulation of shared neural circuits.
Article in Biology of sex differences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Neural and behavioral responses to reproductive signals in male chorus frogs.The Journal of experimental biology · 2026Article
- Prevalence of Same-Sex Sexual Behavior in Termites: Persistence Under Mate-Seeking Stress Absence.Insects · 2026Article
- Sperm function is required for suppressing locomotor activity of C. elegans hermaphrodites.PloS one · 2024Article
- Article
- An auditory-responsive interneuron descending from the cricket brain: a new element in the auditory pathway.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2022Article
- Sex differences in head-fixed voluntary running behavior in C57BL/6J mice.The European journal of neuroscience · 2020Article
- Characterization of the First W-Specific Protein-Coding Gene for Sex Identification inFrontiers in genetics · 2020Article
- Male and female cichlid fish show cognitive inhibitory control ability.Scientific reports · 2019Article
- Sexually Dimorphic Regulation of Behavioral States by Dopamine inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- A Single-Neuron Chemosensory Switch Determines the Valence of a Sexually Dimorphic Sensory Behavior.Current biology : CB · 2018Article
- Effects of Estrogens on Central Nervous System Neurotransmission: Implications for Sex Differences in Mental Disorders.Progress in molecular biology and translational science · 2018Review
- Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila.Nature communications · 2017Article
- Metabolic rate and hypoxia tolerance are affected by group interactions and sex in the fruit fly (Biology open · 2017Article
- Concurrent modulation of neuronal and behavioural olfactory responses to sex and host plant cues in a male moth.Proceedings. Biological sciences · 2015Article
- Sex, age, and hunger regulate behavioral prioritization through dynamic modulation of chemoreceptor expression.Current biology : CB · 2014Article
- Octopamine neuromodulation regulates Gr32a-linked aggression and courtship pathways in Drosophila males.PLoS genetics · 2014Article
- Distributed effects of biological sex define sex-typical motor behavior in Caenorhabditis elegans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- PDF-1 neuropeptide signaling modulates a neural circuit for mate-searching behavior in C. elegans.Nature neuroscience · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals prioritize behaviors according to their physiological needs and reproductive goals, selecting a single behavioral strategy from a repertoire of possible responses to any given stimulus. Biological sex influences this decision-making process in significant ways, differentiating the responses animals choose when faced with stimuli ranging from food to conspecifics. We review here recent work in invertebrate models, including C. elegans, Drosophila, and a variety of insects, mollusks and crustaceans, that has begun to offer intriguing insights into the neural mechanisms underlying the sexual modulation of behavioral decision-making. These findings show that an animal's sex can modulate neural function in surprisingly diverse ways, much like internal physiological variables such as hunger or thirst. In the context of homeostatic behaviors such as feeding, an animal's sex and nutritional status may converge on a common physiological mechanism, the functional modulation of shared sensory circuitry, to influence decision-making. Similarly, considerable evidence suggests that decisions on whether to mate or fight with conspecifics are also mediated through sex-specific neuromodulatory control of nominally shared neural circuits. This work offers a new perspective on how sex differences in behavior emerge, in which the regulated function of shared neural circuitry plays a crucial role. Emerging evidence from vertebrates indicates that this paradigm is likely to extend to more complex nervous systems as well. As men and women differ in their susceptibility to a variety of neuropsychiatric disorders affecting shared behaviors, these findings may ultimately have important implications for human health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.