ReviewDevelopmental cognitive neuroscience2011
The physiology of developmental changes in BOLD functional imaging signals.
Review in Developmental cognitive neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
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Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of physiological methods in rodent pharmacological MRI studies.Psychopharmacology · 2015Pooled it
- Using real-time fMRI to influence effective connectivity in the developing emotion regulation network.NeuroImage · 2016Trial
- Developmental human brain connectome from fetal stage to early childhood.Developmental cognitive neuroscience · 2026Review
- 7 Tesla fMRI characterisation of the cortical-depth-dependent BOLD response in early human development.bioRxiv : the preprint server for biology · 2025Article
- Development of perivascular astrocyte processes.Frontiers in neuroscience · 2025Review
- Functional connectivity of the pediatric brain.Neuroradiology · 2024Review
- Characterizing Large-Scale Human Circuit Development with In Vivo Neuroimaging.Cold Spring Harbor perspectives in biology · 2024Review
- Article
- Myelination and excitation-inhibition balance synergistically shape structure-function coupling across the human cortex.Nature communications · 2023Article
- Maturational networks of human fetal brain activity reveal emerging connectivity patterns prior to ex-utero exposure.Communications biology · 2023Article
- Aberrant olfactory network functional connectivity in people with olfactory dysfunction following COVID-19 infection: an exploratory, observational study.EClinicalMedicine · 2023Article
- Physiological and pathological neuronal connectivity in the living human brain based on intracranial EEG signals: the current state of research.Frontiers in network physiology · 2023Review
- Cerebral haemodynamic response to somatosensory stimulation in preterm lambs is enhanced following sildenafil and inhaled nitric oxide administration.Frontiers in physiology · 2023Article
- Real-Time fMRI Neurofeedback Training as a Neurorehabilitation Approach on Depressive Disorders: A Systematic Review of Randomized Control Trials.Journal of clinical medicine · 2022Review
- In Vivo Magnetic Resonance Thermometry for Brain and Body Temperature Variations in Canines under General Anesthesia.Sensors (Basel, Switzerland) · 2022Article
- The amplitude of fNIRS hemodynamic response in the visual cortex unmasks autistic traits in typically developing children.Translational psychiatry · 2022Article
- Developmental patterns of CBF and BOLD responses to visual stimulus.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Article
- Regional Haemodynamic and Metabolic Coupling in Infants.Frontiers in human neuroscience · 2021Article
- Surface-Based Falff: A Potential Novel Biomarker for Prediction of Radiation Encephalopathy in Patients With Nasopharyngeal Carcinoma.Frontiers in neuroscience · 2021Article
18 more citing papers are in PubMed but not listed here.
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3 authors.
Funding
Abstract
BOLD fMRI (blood oxygenation level dependent functional magnetic resonance imaging) is increasingly used to detect developmental changes of human brain function that are hypothesized to underlie the maturation of cognitive processes. BOLD signals depend on neuronal activity increasing cerebral blood flow, and are reduced by neural oxygen consumption. Thus, developmental changes of BOLD signals may not reflect altered information processing if there are concomitant changes in neurovascular coupling (the mechanism by which neuronal activity increases blood flow) or neural energy use (and hence oxygen consumption). We review how BOLD signals are generated, and explain the signalling pathways which convert neuronal activity into increased blood flow. We then summarize in broad terms the developmental changes that the brain's neural circuitry undergoes during growth from childhood through adolescence to adulthood, and present the changes in neurovascular coupling mechanisms and energy use which occur over the same period. This information provides a framework for assessing whether the BOLD changes observed during human development reflect altered cognitive processing or changes in neurovascular coupling and energy use.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.