ArticleMolecular plant pathology2012
Generation of transgenic plantain (Musa spp.) with resistance to plant pathogenic nematodes.
Article in Molecular plant pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 69 citations in OpenAlex.
- Banana breeding by genome design.Journal of integrative plant biology · 2025Review
- Precision genetics tools for genetic improvement of banana.The plant genome · 2024Review
- Phytoparasitic Nematodes ofPlants (Basel, Switzerland) · 2024Review
- Transgenic East African Highland Banana Plants Are Protected againstInternational journal of molecular sciences · 2023Article
- Identification of cytochrome P450 gene family and functional analysis ofFrontiers in plant science · 2023Article
- Field test of Easter lilies transformed with a rice cystatin gene for root lesion nematode resistance.Frontiers in plant science · 2023Article
- Review
- Understanding Molecular Plant-Nematode Interactions to Develop Alternative Approaches for Nematode Control.Plants (Basel, Switzerland) · 2022Review
- FMRFamide-Like Peptide 22 Influences the Head Movement, Host Finding, and Infection ofFrontiers in plant science · 2021Article
- Simultaneous RNAi Knockdown of Three FMRFamide-Like Peptide Genes,Frontiers in microbiology · 2020Article
- RNAi-mediated protection against banana diseases and pests.3 Biotech · 2019Review
- Resistance to Cereal Cyst Nematodes in Wheat and Barley: An Emphasis on Classical and Modern Approaches.International journal of molecular sciences · 2019Review
- Article
- Genetic engineering strategies for biotic and abiotic stress tolerance and quality enhancement in horticultural crops: a comprehensive review.3 Biotech · 2017Review
- Genetically engineered bananas resistant to Xanthomonas wilt disease and nematodes.Food and energy security · 2017Review
- Transgenic Strategies for Enhancement of Nematode Resistance in Plants.Frontiers in plant science · 2017Review
- Functional proteomics-aided selection of protease inhibitors for herbivore insect control.Scientific reports · 2016Article
- The ZmRCP-1 promoter of maize provides root tip specific expression of transgenes in plantain.Journal of biological research (Thessalonike, Greece) · 2016Article
- Expression of a Cystatin Transgene in Eggplant Provides Resistance to Root-knot Nematode, Meloidogyne incognita.Frontiers in plant science · 2016Article
- Identification of Ramie Genes in Response to Pratylenchus coffeae Infection Challenge by Digital Gene Expression Analysis.International journal of molecular sciences · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
Abstract
Plant parasitic nematodes impose a severe constraint on plantain and banana productivity; however, the sterile nature of many cultivars precludes conventional breeding for resistance. Transgenic plantain cv. Gonja manjaya (Musa AAB) plants, expressing a maize cystatin that inhibits nematode digestive cysteine proteinases and a synthetic peptide that disrupts nematode chemoreception, were assessed for their ability to resist nematode infection. Lines were generated that expressed each gene singly or both together in a stacked defence. Nematode challenge with a single species or a mixed population identified 10 lines with significant resistance. The best level of resistance achieved against the major pest species Radopholus similis was 84% ± 8% for the cystatin, 66% ± 14% for the peptide and 70% ± 6% for the dual defence. In the mixed population, trial resistance was also demonstrated to Helicotylenchus multicinctus. A fluorescently labelled form of the chemodisruptive peptide underwent retrograde transport along certain sensory dendrites of R. similis as required to disrupt chemoreception. The peptide was degraded after 30 min in simulated intestinal fluid or boiling water and after 1 h in nonsterile soil. In silico sequence analysis suggests that the peptide is not a mammalian antigen. This work establishes the mode of action of a novel nematode defence, develops the evidence for its safe and effective deployment against multiple nematode species and identifies transgenic plantain lines with a high level of resistance for a proposed field trial.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.