ArticleFrontiers in integrative neuroscience2012
Acquisition of "Start" and "Stop" response thresholds in peak-interval timing is differentially sensitive to protein synthesis inhibition in the dorsal and ventral striatum.
Article in Frontiers in integrative neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 67 citations in OpenAlex.
- Timing and Intertemporal Choice Behavior in the Valproic Acid Rat Model of Autism Spectrum Disorder.Journal of autism and developmental disorders · 2022Article
- Temporal prediction error triggers amygdala-dependent memory updating in appetitive operant conditioning in rats.Frontiers in behavioral neuroscience · 2022Article
- The dorsal hippocampus is required for the formation of long-term duration memories in rats.The European journal of neuroscience · 2021Article
- Timing behavior in genetic murine models of neurological and psychiatric diseases.Experimental brain research · 2021Review
- Temporal Learning Among Prefrontal and Striatal Ensembles.Cerebral cortex communications · 2020Article
- Internal Clocks, mGluR7 and Microtubules: A Primer for the Molecular Encoding of Target Durations in Cerebellar Purkinje Cells and Striatal Medium Spiny Neurons.Frontiers in molecular neuroscience · 2019Article
- Probabilistic Information Modulates the Timed Response Inhibition Deficit in Aging Mice.Frontiers in behavioral neuroscience · 2019Article
- Changes in Magnitude and Variability of Corticospinal Excitability During Rewarded Time-Sensitive Behavior.Frontiers in behavioral neuroscience · 2019Article
- Corticospinal excitability is modulated by temporal feedback gaps.Neuroreport · 2018Article
- Functional coding variation in the presynaptic dopamine transporter associated with neuropsychiatric disorders drives enhanced motivation and context-dependent impulsivity in mice.Behavioural brain research · 2018Article
- Recollection-dependent memory for event duration in large-scale spatial navigation.Learning & memory (Cold Spring Harbor, N.Y.) · 2017Article
- Updating temporal expectancy of an aversive event engages striatal plasticity under amygdala control.Nature communications · 2017Article
- Temporal averaging across multiple response options: insight into the mechanisms underlying integration.Animal cognition · 2016Article
- Cognitive Aging and Time Perception: Roles of Bayesian Optimization and Degeneracy.Frontiers in aging neuroscience · 2016Review
- Comparison of interval timing behaviour in mice following dorsal or ventral hippocampal lesions with mice having δ-opioid receptor gene deletion.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Article
- Prospective and retrospective duration memory in the hippocampus: is time in the foreground or background?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- Rationalizing Decision-Making: Understanding the Cost and Perception of Time.Timing & time perception reviews · 2014Article
- Dissociations between interval timing and intertemporal choice following administration of fluoxetine, cocaine, or methamphetamine.Behavioural processes · 2014Article
- Implicit and explicit timing in oculomotor control.PloS one · 2014Article
- Hippocampus, time, and memory--a retrospective analysis.Behavioral neuroscience · 2013Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Time-based decision-making in peak-interval timing procedures involves the setting of response thresholds for the initiation ("Start") and termination ("Stop") of a response sequence that is centered on a target duration. Using intracerebral infusions of the protein synthesis inhibitor anisomycin, we report that the acquisition of the "Start" response depends on normal functioning (including protein synthesis) in the dorsal striatum (DS), but not the ventral striatum (VS). Conversely, disruption of the VS, but not the DS, impairs the acquisition of the "Stop" response. We hypothesize that the dorsal and ventral regions of the striatum function as a competitive neural network that encodes the temporal boundaries marking the beginning and end of a timed response sequence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.