Evidence map›Paper›PMID 22434864›Full record

ArticleInternational journal of epidemiology2012

The use of ethnically specific norms for ventilatory function in African-American and white populations.

P G J Burney, R L Hooper

Open access · bronzeAbstract read
In one paragraph

Article in International journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

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  12. Implications of Race Adjustment in Lung-Function Equations.The New England journal of medicine · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

P G J BurneyNational Heart & Lung Institute, Imperial College, London, UK. p.burney@imperial.ac.uk
R L Hooper
Queen Mary University of London · GB

Funding

Department of Health 0120016
6 · The paper itself

Abstract

backgroundIn the USA, different standards are usually set for spirometric values in African-American and white populations. It is unclear to what extent the lower lung function found in African-Americans is 'normal' in the sense of having no adverse consequences.

methodsAfrican-American and white participants in the Atherosclerosis Risk in Communities (ARIC) limited access data set, from four communities in the USA had spirometric testing at baseline beginning in 1986 and were followed up to assess survival to the end of 2002.

resultsForced Expiratory Volume in 1 s (FEV(1)) and Forced Vital Capacity (FVC) were lower in the African-American than the white sample both for men and women and adjustment for potential confounders had little effect on the estimated difference {difference in FVC after adjustment: men, -0.68 l [95% confidence interval (95% CI) -0.75 to -0.61]; women, -0.41 l (95%CI -0.45 to -0.36)}. The FEV(1)/FVC ratio was slightly greater among African-American than white participants [difference: men, 1.5% (95%CI 0.7-2.1); women, 1.7% (95%CI 1.1-2.2)]. After adjustment for age and height, survival was similar in each ethnic group for any given level of FVC before and after adjustment for potential confounders. The hazard ratio for African-American compared with white participants was 1.24 for men (95% CI 0.91-1.69) and 0.96 for women (95% CI 0.66-1.38).

conclusionsA given FVC has the same prognostic significance for 'normal' African-American and white participants. It is inappropriate to use ethnic norms when assessing prognosis.

Indexed as

Age FactorsAtherosclerosisBlack or African AmericanBody Weights and MeasuresFemaleForced Expiratory VolumeHumansMaleMiddle AgedReference StandardsRespiratory Function TestsSex FactorsSocioeconomic FactorsUnited StatesWhite People

Identifiers

PMID22434864
PMCPMC3396311
OpenAlexW2171240294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.