Evidence map›Paper›PMID 22434860›Full record

ArticleInternational journal of epidemiology2013

Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa.

Matthew P Fox, Mhairi Maskew, A Patrick MacPhail, Lawrence Long, Alana T Brennan, Daniel Westreich, William B MacLeod, Pappie Majuba, Ian M Sanne

Abstract read
In one paragraph

Article in International journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew P FoxCentre for Global Health and Development, Boston University, Boston, MA, USA.
Mhairi Maskew
A Patrick MacPhail
Lawrence Long
Alana T Brennan
Daniel Westreich
William B MacLeod
Pappie Majuba
Ian M Sanne

Funding

Training in Sexually Transmitted Infections and HIVT32AI007001 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SENA-SOBERANO, ARLENE C. · 1985 to 2025
$10.9M
Pregnancy and Response to Antiretroviral Therapy in South AfricaR00HD063961 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WESTREICH, DANIEL J · 2010 to 2012
$687k
Rates, Predictors and Mortality Impact of Losses from HIV Care in South AfricaK01AI083097 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FOX, MATTHEW ALEXANDER PEASE · 2009 to 2013
$615k
NIAID NIH HHS 5 T32 AI 07001-32NIAID NIH HHS K01 AI083097NIAID NIH HHS K01AI083097NIAID NIH HHS T32 AI007001NICHD NIH HHS 4 R00-HD-06-3961-02NICHD NIH HHS R00 HD063961
6 · The paper itself

Abstract

The Themba Lethu Clinical Cohort was established in 2004 to allow large patient-level analyses from a single HIV treatment site to evaluate National Treatment Guidelines, answer questions of national and international policy relevance and to combine an economic and epidemiologic focus on HIV research. The current objectives of the Themba Lethu Clinical Cohort analyses are to: (i) provide cohort-level information on the outcomes of HIV treatment; (ii) evaluate aspects of HIV care and treatment that have policy relevance; (iii) evaluate the cost and cost-effectiveness of different approaches to HIV care and treatment; and (iv) provide a platform for studies on improving HIV care and treatment. Since 2004, Themba Lethu Clinic has enrolled approximately 30,000 HIV-positive patients into its HIV care and treatment programme, over 21,000 of whom have received anti-retroviral therapy since being enrolled. Patients on treatment are typically seen at least every 3 months with laboratory monitoring every 6 months to 1 year. The data collected include demographics, clinical visit data, laboratory data, medication history and clinical diagnoses. Requests for collaborations on analyses can be submitted to our data centre.

Indexed as

AdultAnti-HIV AgentsCD4 Lymphocyte CountFemaleHIV InfectionsHumansMalePractice Guidelines as TopicProgram EvaluationSocioeconomic FactorsSouth AfricaTreatment OutcomeViral LoadAnti-HIV Agents

Identifiers

PMID22434860
PMCPMC3619949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.