ArticleDatabase : the journal of biological databases and curation2012
Aptamer Base: a collaborative knowledge base to describe aptamers and SELEX experiments.
Article in Database : the journal of biological databases and curation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- AptViralDB: A repository of experimentally validated antiviral aptamers.Molecular therapy. Nucleic acids · 2026Review
- APDB: A Large-Scale Repository of Predicted 2D and 3D Aptamer Structures.Journal of chemical information and modeling · 2026Article
- Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers.Nucleic acids research · 2026Article
- Interpretable prediction and generation of ASC-speck aptamers using multiscale deep biological learning models.Bioinformatics advances · 2026Article
- Benchmarking the Base Randomization Algorithm as a Possible Tool for the Initial Step of Generating a Virtual RNA Aptamers Library.Biotech (Basel (Switzerland)) · 2025Article
- APIPred: An XGBoost-Based Method for Predicting Aptamer-Protein Interactions.Journal of chemical information and modeling · 2024Article
- UTexas Aptamer Database: the collection and long-term preservation of aptamer sequence information.Nucleic acids research · 2024Article
- AptaTrans: a deep neural network for predicting aptamer-protein interaction using pretrained encoders.BMC bioinformatics · 2023Article
- Smart nanoparticles for cancer therapy.Signal transduction and targeted therapy · 2023Review
- The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers.Pharmaceuticals (Basel, Switzerland) · 2023Article
- In vitro selection of aptamers and their applications.Nature reviews. Methods primers · 2023Article
- Could artificial intelligence revolutionize the development of nanovectors for gene therapy and mRNA vaccines?Nano today · 2022Article
- Artificial Intelligence in Aptamer-Target Binding Prediction.International journal of molecular sciences · 2021Review
- AptaNet as a deep learning approach for aptamer-protein interaction prediction.Scientific reports · 2021Article
- Article
- CRISPR-Mediated Isogenic Cell-SELEX Approach for Generating Highly Specific Aptamers Against Native Membrane Proteins.Cellular and molecular bioengineering · 2020Article
- High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes.Scientific reports · 2020Article
- PPAI: a web server for predicting protein-aptamer interactions.BMC bioinformatics · 2020Article
- An oligosorbent-based aptamer affinity column for selective extraction of aflatoxin BMikrochimica acta · 2017Article
- Aptamer Bioinformatics.International journal of molecular sciences · 2017Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past several decades, rapid developments in both molecular and information technology have collectively increased our ability to understand molecular recognition. One emerging area of interest in molecular recognition research includes the isolation of aptamers. Aptamers are single-stranded nucleic acid or amino acid polymers that recognize and bind to targets with high affinity and selectivity. While research has focused on collecting aptamers and their interactions, most of the information regarding experimental methods remains in the unstructured and textual format of peer reviewed publications. To address this, we present the Aptamer Base, a database that provides detailed, structured information about the experimental conditions under which aptamers were selected and their binding affinity quantified. The open collaborative nature of the Aptamer Base provides the community with a unique resource that can be updated and curated in a decentralized manner, thereby accommodating the ever evolving field of aptamer research. DATABASE URL: http://aptamer.freebase.com.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.