Evidence map›Paper›PMID 22434447›Full record

ArticleAmbio2012

Genetic engineering of cyanobacteria to enhance biohydrogen production from sunlight and water.

Hajime Masukawa, Masaharu Kitashima, Kazuhito Inoue, Hidehiro Sakurai, Robert P Hausinger

Open access · bronzeAbstract read
In one paragraph

Article in Ambio, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 46 citations in OpenAlex.

  1. Effects of Photosynthesis Inhibitors on HPlants (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Pressurized Martian-Like Pure CO2 Atmosphere Supports Strong Growth of Cyanobacteria, and Causes Significant Changes in their Metabolism.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2016
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hajime MasukawaPRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan. jimimasu@gmail.com
Masaharu Kitashima
Kazuhito Inoue
Hidehiro Sakurai
Robert P Hausinger
Kanagawa University · JPJapan Science and Technology Agency · JPMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To mitigate global warming caused by burning fossil fuels, a renewable energy source available in large quantity is urgently required. We are proposing large-scale photobiological H(2) production by mariculture-raised cyanobacteria where the microbes capture part of the huge amount of solar energy received on earth's surface and use water as the source of electrons to reduce protons. The H(2) production system is based on photosynthetic and nitrogenase activities of cyanobacteria, using uptake hydrogenase mutants that can accumulate H(2) for extended periods even in the presence of evolved O(2). This review summarizes our efforts to improve the rate of photobiological H(2) production through genetic engineering. The challenges yet to be overcome to further increase the conversion efficiency of solar energy to H(2) also are discussed.

Indexed as

Genetic EngineeringSolar EnergyCatalytic DomainCyanobacteriaHydrogenNitrogenasePhotochemistryWaterHydrogenNitrogenaseWater

Identifiers

PMID22434447
PMCPMC3357757
OpenAlexW2051865780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.