Evidence map›Paper›PMID 22434203›Full record

SynthesisOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2012

A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis.

S Lekamwasam, J D Adachi, D Agnusdei, J Bilezikian, S Boonen, F Borgström, C Cooper, A Diez Perez, R Eastell, L C Hofbauer and 17 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Effects of glucocorticoids on osteoporosis in rheumatoid arthritis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
  4. European guidance for the diagnosis and management of osteoporosis in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Guideline
  5. Pooled it
  6. Bisphosphonates for steroid-induced osteoporosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  7. Fracture risk in oral glucocorticoid users: a Bayesian meta-regression leveraging control arms of osteoporosis clinical trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Pooled it
  8. Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2015
    Guideline
  9. Pooled it
  10. European guidance for the diagnosis and management of osteoporosis in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Guideline
  11. Trial
  12. Trial
  13. Management of glucocorticoid-induced osteoporosis in rheumatic diseases.Best practice & research. Clinical rheumatology · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Rapid reduction in fracture risk after the discontinuation of long-term oral glucocorticoid therapy: a retrospective cohort study using a nationwide health insurance claims database in Japan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  20. Article

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

S LekamwasamDepartment of Medicine, Faculty of Medicine, Centre for Metabolic Bone Diseases, Galle, Sri Lanka.
J D Adachi
D Agnusdei
J Bilezikian
S Boonen
F Borgström
C Cooper
A Diez Perez
R Eastell
L C Hofbauer
J A Kanis
B L Langdahl
O Lesnyak
R Lorenc
E McCloskey
O D Messina
N Napoli
B Obermayer-Pietsch
S H Ralston
P N Sambrook
S Silverman
M Sosa
J Stepan
G Suppan
D A Wahl
J E Compston
Joint IOF-ECTS GIO Guidelines Working Group

Funding

Medical Research Council MC_U147585824Medical Research Council MC_UP_A620_1014
6 · The paper itself

Abstract

unlabelledThis paper provides a framework for the development of national guidelines for the management of glucocorticoid-induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer.

introductionThe need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. METHODS AND

resultsThe epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review.

conclusionsGuidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of each country.

Indexed as

Practice Guidelines as TopicAgedAged, 80 and overBone DensityBone Density Conservation AgentsFemaleGlucocorticoidsHumansMaleMiddle AgedOsteoporosisRisk AssessmentRisk FactorsTreatment OutcomeBone Density Conservation AgentsGlucocorticoids

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.