Evidence map›Paper›PMID 22434049›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2012

Functional imaging techniques in hepatocellular carcinoma.

V Goh, D Sarker, S Osmany, G J R Cook

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. The Imaging Value ofMolecular imaging and biology · 2025
    Article
  2. Comparison ofCancer science · 2025
    Article
  3. Molecular imaging and biology · 2025
    Article
  4. Frontiers in oncology · 2025
    Article
  5. Article
  6. Is System xCancers · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Frontiers in oncology · 2021
    Article
  11. Review
  12. Intravoxel incoherent motion MRI as a biomarker of sorafenib treatment for advanced hepatocellular carcinoma: a pilot study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

V GohDivision of Imaging Sciences and Biomedical Engineering, Kings College London, London, UK.
D Sarker
S Osmany
G J R Cook

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel biological therapies, including tyrosine kinase inhibitors such as sorafenib, improve the survival of patients with unresectable hepatocellular carcinoma. However, assessment of therapeutic efficacy remains challenging with conventional imaging techniques such as ultrasonography, CT or MRI that predominantly rely on size change to detect a treatment response. A beneficial tumour effect may go unrecognized in some patients who do not show tumour shrinkage and conversely, some patients may be maintained on treatment that is not active. This paper explores the use of functional imaging methods that are showing promise in the assessment of hepatocellular carcinoma.

Indexed as

AnimalsCarcinoma, HepatocellularDiagnostic ImagingHumansLiver NeoplasmsNeovascularization, PathologicRadiographyRadionuclide ImagingUltrasonography

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.