ArticleBMC genomics2012
Genome-wide microarray analysis of tomato roots showed defined responses to iron deficiency.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 84 citations in OpenAlex.
- Arbuscular Mycorrhiza Modulates Iron Distribution and Vacuolar Iron Transporter Expression in Tomato, Whereas Iron Limitation Reduces Mycorrhization.Plant, cell & environment · 2026Article
- New molecular components of high and low affinity iron import systems in Drosophila.Nature communications · 2025Article
- Harnessing the Potential of CRISPR/Cas in Targeted Alfalfa Improvement for Stress Resilience.International journal of molecular sciences · 2025Review
- A multi-omics insight on the interplay between iron deficiency and N forms in tomato.Frontiers in plant science · 2024Article
- Evidence ThatPlants (Basel, Switzerland) · 2023Article
- Recent advancements in multifaceted roles of flavonoids in plant-rhizomicrobiome interactions.Frontiers in plant science · 2023Review
- Nodulating white lupins take advantage of the reciprocal interplay between N and P nutritional responses.Physiologia plantarum · 2022Article
- Genome-Wide Association Analysis Reveals the Genetic Basis of Iron-Deficiency Stress Tolerance in Maize.Frontiers in plant science · 2022Article
- Iron deficiency triggered transcriptome changes in bread wheat.Computational and structural biotechnology journal · 2020Article
- Common and specific responses to iron and phosphorus deficiencies in roots of apple tree (Malus × domestica).Plant molecular biology · 2019Article
- Transcriptome analysis in Malus halliana roots in response to iron deficiency reveals insight into sugar regulation.Molecular genetics and genomics : MGG · 2018Article
- Article
- Transcriptional and physiological analyses of Fe deficiency response in maize reveal the presence of Strategy I components and Fe/P interactions.BMC genomics · 2017Article
- AhIRT1 and AhNRAMP1 metal transporter expression correlates with Cd uptake in peanuts under iron deficiency.PloS one · 2017Article
- The Understanding of the Plant Iron Deficiency Responses in Strategy I Plants and the Role of Ethylene in This Process by Omic Approaches.Frontiers in plant science · 2017Review
- Arabidopsis Glutaredoxin S17 Contributes to Vegetative Growth, Mineral Accumulation, and Redox Balance during Iron Deficiency.Frontiers in plant science · 2017Article
- Insights into Resistance to Fe Deficiency Stress from a Comparative Study ofFrontiers in plant science · 2017Article
- Early transcriptomic response to Fe supply in Fe-deficient tomato plants is strongly influenced by the nature of the chelating agent.BMC genomics · 2016Article
- Comparative transcriptional profiling of orange fruit in response to the biocontrol yeast Kloeckera apiculata and its active compounds.BMC genomics · 2016Article
- Transcriptional Characterization of a Widely-Used Grapevine Rootstock Genotype under Different Iron-Limited Conditions.Frontiers in plant science · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlants react to iron deficiency stress adopting different kind of adaptive responses. Tomato, a Strategy I plant, improves iron uptake through acidification of rhizosphere, reduction of Fe3+ to Fe2+ and transport of Fe2+ into the cells. Large-scale transcriptional analyses of roots under iron deficiency are only available for a very limited number of plant species with particular emphasis for Arabidopsis thaliana. Regarding tomato, an interesting model species for Strategy I plants and an economically important crop, physiological responses to Fe-deficiency have been thoroughly described and molecular analyses have provided evidence for genes involved in iron uptake mechanisms and their regulation. However, no detailed transcriptome analysis has been described so far.
resultsA genome-wide transcriptional analysis, performed with a chip that allows to monitor the expression of more than 25,000 tomato transcripts, identified 97 differentially expressed transcripts by comparing roots of Fe-deficient and Fe-sufficient tomato plants. These transcripts are related to the physiological responses of tomato roots to the nutrient stress resulting in an improved iron uptake, including regulatory aspects, translocation, root morphological modification and adaptation in primary metabolic pathways, such as glycolysis and TCA cycle. Other genes play a role in flavonoid biosynthesis and hormonal metabolism.
conclusionsThe transcriptional characterization confirmed the presence of the previously described mechanisms to adapt to iron starvation in tomato, but also allowed to identify other genes potentially playing a role in this process, thus opening new research perspectives to improve the knowledge on the tomato root response to the nutrient deficiency.
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