Evidence map›Paper›PMID 22432771›Full record

ReviewAutoimmunity2012

B effector cells in rheumatoid arthritis and experimental arthritis.

Alison Finnegan, Susan Ashaye, Keith M Hamel

Open access · greenAbstract readReview
In one paragraph

Review in Autoimmunity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  18. Autoimmunity in 2012.Clinical reviews in allergy & immunology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alison FinneganDepartment of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, Illinois 60612, USA. Alison_Finnegan@rush.edu
Susan Ashaye
Keith M Hamel
Rush University Medical Center · USUniversity of Chicago · US

Funding

RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
B CELL FUNCTION IN AUTOIMMUNE ARTHRITISR01AR047657 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI FINNEGAN, ALISON · 2002 to 2011
$3.0M
Cytokine Regulation in Experimental ArthritisR01AR056999 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI FINNEGAN, ALISON · 2009 to 2013
$1.6M
NHLBI NIH HHS NIHT32HL007605NHLBI NIH HHS T32 HL007605NIAMS NIH HHS R01AR04657NIAMS NIH HHS R01 AR047657NIAMS NIH HHS R01 AR056999NIAMS NIH HHS R01AR056999
6 · The paper itself

Abstract

Rheumatoid arthritis is a chronic autoimmune immune disease affecting approximately 1% of the population. There has been a renewed interest in the role of B cells in rheumatoid arthritis based on the evidence that B cell depletion therapy is effective in the treatment of disease. This review summarizes the current knowledge of the mechanisms by which B cells contribute to autoimmune arthritis including roles as autoantibody producing cells, antigen-presenting cells, cytokine producing cells, and regulatory cells.

Indexed as

AnimalsAntigen-Presenting CellsArthritis, ExperimentalArthritis, RheumatoidAutoantibodiesAutoimmune DiseasesAutoimmunityB-Lymphocyte SubsetsCytokinesHumansImmune ToleranceAutoantibodiesCytokines

Identifiers

PMID22432771
PMCPMC3638788
OpenAlexW1969235022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.