Evidence map›Paper›PMID 22432581›Full record

ReviewAnnual review of chemical and biomolecular engineering2010

Theoretical aspects of immunity.

Michael W Deem, Pooya Hejazi

Abstract readReview
In one paragraph

Review in Annual review of chemical and biomolecular engineering, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael W DeemDepartment of Bioengineering and Physics, Rice University, Houston, TX 77005, USA. mwdeem@rice.edu
Pooya Hejazi

Funding

NANOBIOLOGY INSTITUTIONAL TRAINING GRANT(RMI)R90DK071504 · NIDDK · UNIVERSITY OF HOUSTON · PI PETTITT, BERNARD MONTGOMERY · 2004 to 2008
$1.3M
NIDDK NIH HHS R90 DK071504
6 · The paper itself

Abstract

The immune system recognizes a myriad of invading pathogens and their toxic products. It does so with a finite repertoire of antibodies and T cell receptors. We here describe theories that quantify the dynamics of the immune system. We describe how the immune system recognizes antigens by searching the large space of receptor molecules. We consider in some detail the theories that quantify the immune response to influenza and dengue fever. We review theoretical descriptions of the complementary evolution of pathogens that occurs in response to immune system pressure. Methods including bioinformatics, molecular simulation, random energy models, and quantum field theory contribute to a theoretical understanding of aspects of immunity.

Indexed as

ImmunityModels, BiologicalAnimalsBiological EvolutionComputational BiologyDengueDengue VirusHumansImmune SystemInfluenza A virusInfluenza, HumanModels, Molecular

Identifiers

PMID22432581
PMCPMC4487771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.