ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2012
Prevalence and factors associated with sleep disturbances among early-treated HIV-infected persons.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00893815 (Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence and moderating factors of sleep disturbances in people living with HIV: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- A multilevel examination of sleep, depression, and quality of life in people living with HIV/AIDS.Journal of health psychology · 2020Trial
- Sleep health epidemiology in adults with and without HIV in Mwanza, Tanzania: Baseline results from an ongoing cohort study.Sleep epidemiology · 2026Article
- Sleep Disorders Are Associated with Mental Health, Quality of Life and Stigma in an Italian Cohort of People Living with HIV.Brain sciences · 2025Article
- Associations between multimorbidity burden and objective and patient-reported sleep outcomes among people with HIV.AIDS (London, England) · 2025Article
- Article
- Sleep quality mediates the effect of medical social support on depression symptoms in patients with HIV/AIDS.BMC public health · 2024Article
- Sleep traits and associated factors among people living with HIV/AIDS in Iran: a two-step clustering analysis.Scientific reports · 2024Article
- Sleep deficiency among people living with human immunodeficiency virus: A growing challenge.HIV medicine · 2024Review
- Prevalence of Risk Factors Associated With Poor Quality of Sleep in People Living with HIV and the Correlation between Quality of Sleep and Cd4+ T Lymphocyte Reconstitution: A Cross-Sectional Study from Turkey.Current HIV research · 2024Article
- Poor sleep quality and associated factors among HIV-positive and negative postpartum women in Addis Ababa, Ethiopia: a comparative cross-sectional study.Frontiers in psychiatry · 2024Article
- Association between psychological discomforts and sleep quality among people living with HIV/AIDS.AIDS research and therapy · 2023Article
- Observational
- Poor subjective sleep reported by people living with HIV is associated with impaired working memory.NeuroImmune pharmacology and therapeutics · 2023Article
- Article
- Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop.AIDS research and human retroviruses · 2023Article
- Sleep Disturbances and Chronic Pain in People with HIV: Implications for HIV-Associated Neurocognitive Disorders.Current sleep medicine reports · 2022Article
- Poor sleep quality and associated factors among people attending anti-retroviral treatment clinic at Finote selam general hospital, Amhara, Ethiopia.Sleep medicine: X · 2022Article
- Objective and subjective sleep measures are associated with neurocognition in aging adults with and without HIV.The Clinical neuropsychologist · 2022Article
- Observational
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10 authors.
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Abstract
backgroundSleep disturbances are reportedly common among persons infected with human immunodeficiency virus (HIV), but recent data, including comparisons with HIV-uninfected persons, are limited.
methodsWe performed a cross-sectional study among early-treated HIV-infected military beneficiaries (n = 193) to determine the prevalence and factors associated with insomnia (Pittsburgh Sleep Quality Index [PSQI]) and daytime sleepiness (Epworth Sleepiness Scale [ESS]). Data were compared with HIV-uninfected persons (n = 50) matched by age, sex, race or ethnicity, and military rank.
resultsForty-six percent of HIV-infected persons had insomnia (PSQI >5), and 30% reported daytime drowsiness (ESS ≥10). The prevalence of insomnia and daytime sleepiness was not significantly higher compared with the HIV-uninfected group (38% [P = .30] and 20% [P = .18], respectively). In the multivariate model, factors associated with insomnia among HIV infected patients included depression (odds ratio [OR], 16.8; 95% confidence interval [CI], 2.0-142.1; P = .01), increased waist size (OR, 2.7; 95% CI, 1.4-5.1; P = .002), and fewer years of education (OR, 0.8; 95% CI, .7-.95; P = .006). Neurocognitive impairment (diagnosed in 19% of HIV-infected participants) was not associated with insomnia; however, HIV-infected persons with insomnia were 3.1-fold more likely to have a decline in activities of daily living than those without insomnia (23% vs 9%; P = .01). Only 18% of HIV-infected persons reported using a sleep medication at least weekly.
conclusionsHIV-infected persons have a high prevalence of insomnia, but among an early-treated cohort this rate was not significantly higher compared with HIV-uninfected persons. Factors associated with insomnia among HIV-infected patients include depression and increased waist size. Prompt diagnosis and treatment of sleep disturbances are advocated and may improve quality of life.
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