ArticleAmerican journal of epidemiology2012
Derivation and validation of the Denver Human Immunodeficiency Virus (HIV) risk score for targeted HIV screening.
Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02959684 (Strategic Screening for Infectious Diseases), which is not on this map. Cited by 51 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Strategic Screening for Infectious Diseases (Tuberculosis, HIV, HBV, HCV) Amongst Migrants in France
Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Risk prediction models for targeted testing of HIV, hepatitis B and hepatitis C: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Performance of HIV Infection Prediction Models in Men Who Have Sex with Men: A Systematic Review and Meta-Analysis.Archives of sexual behavior · 2023Pooled it
- HIV testing within general practices in Europe: a mixed-methods systematic review.BMC public health · 2018Pooled it
- Comparison of HIV Screening Strategies in the Emergency Department: A Randomized Clinical Trial.JAMA network open · 2021Trial
- High HIV/STI Test Acceptance Through a Behavioral Health Encounter in Latino Immigrants with Substance Use and Mental Health Problems.AIDS and behavior · 2019Trial
- Outcome of an HIV education program for primary care providers: Screening and late diagnosis rates.PloS one · 2019Trial
- Trial
- The impact of nurse-driven targeted HIV screening in 8 emergency departments: study protocol for the DICI-VIH cluster-randomized two-period crossover trial.BMC infectious diseases · 2016Trial
- Patient choice in opt-in, active choice, and opt-out HIV screening: randomized clinical trial.BMJ (Clinical research ed.) · 2016Trial
- Randomized comparison of universal and targeted HIV screening in the emergency department.Journal of acquired immune deficiency syndromes (1999) · 2013Trial
- Comparison of enhanced targeted rapid HIV screening using the Denver HIV risk score to nontargeted rapid HIV screening in the emergency department.Annals of emergency medicine · 2013Trial
- Correlates of HIV and STI Testing in Rural Southern Substance Using-Men who have Sex with Men: A Behavioral Model for Health Services Use Approach.AIDS and behavior · 2026Article
- Diagnostic performance of HIV risk assessment tools for identifying pre-exposure prophylaxis candidates: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Self-Perception of Risk for HIV Acquisition and Calculated Risk for HIV Acquisition Among Active Duty Air Force Members With Newly Diagnosed HIV Infection.Military medicine · 2024Article
- Developing HIV risk prediction tools in four African settings.Tropical medicine & international health : TM & IH · 2023Article
- Age-Restriction of a Validated Risk Scoring Tool Better Predicts HIV Acquisition in South African Women: CAPRISA 004.AIDS and behavior · 2022Article
- Screening Adults for HIV Testing in the Outpatient Department: An Assessment of Tool Performance in Malawi.AIDS and behavior · 2022Article
- Prediction Model for the Risk of HIV Infection among MSM in China: Validation and Stability.International journal of environmental research and public health · 2022Article
- Predicting the risk of HIV infection among internal migrant MSM in China: An optimal model based on three variable selection methods.Frontiers in public health · 2022Article
- Derivation of an HIV Risk Score for African Women Who Engage in Sex Work.AIDS and behavior · 2021Article
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Authors and funding
11 authors.
Funding
Abstract
Targeted screening remains an important approach to human immunodeficiency virus (HIV) testing. The authors aimed to derive and validate an instrument to accurately identify patients at risk for HIV infection, using patient data from a metropolitan sexually transmitted disease clinic in Denver, Colorado (1996-2008). With multivariable logistic regression, they developed a risk score from 48 candidate variables using newly identified HIV infection as the outcome. Validation was performed using an independent population from an urban emergency department in Cincinnati, Ohio. The derivation sample included 92,635 patients; 504 (0.54%) were diagnosed with HIV infection. The validation sample included 22,983 patients; 168 (0.73%) were diagnosed with HIV infection. The final score included age, gender, race/ethnicity, sex with a male, vaginal intercourse, receptive anal intercourse, injection drug use, and past HIV testing, and values ranged from -14 to +81. For persons with scores of <20, 20-29, 30-39, 40-49, and ≥50, HIV prevalences were 0.31% (95% confidence interval (CI): 0.20, 0.45) (n = 27/8,782), 0.41% (95% CI: 0.29, 0.57) (n = 36/8,677), 0.99% (95% CI: 0.63, 1.47) (n = 24/2,431), 1.59% (95% CI: 1.02, 2.36) (n = 24/1,505), and 3.59% (95% CI: 2.73, 4.63) (n = 57/1,588), respectively. The risk score accurately categorizes patients into groups with increasing probabilities of HIV infection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.