Trial reportThe Journal of physiology2012
The resonant component of human physiological hand tremor is altered by slow voluntary movements.
Trial report in The Journal of physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Overcoming the impact of physiologic tremors in ophthalmology.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Pooled it
- Need for mechanically and ergonomically enhanced tremor-suppression orthoses for the upper limb: a systematic review.Journal of neuroengineering and rehabilitation · 2019Pooled it
- Smartwatch-based wrist tremor assessment in neurosurgical simulator training.Scientific reports · 2025Article
- Empirical classification of fatigue-induced physiological tremor in robot-assisted manipulation tasks using BiLSTM-GRU network.Frontiers in rehabilitation sciences · 2025Article
- The Effects of Hand Tremors on the Shooting Performance of Air Pistol Shooters with Different Skill Levels.Sensors (Basel, Switzerland) · 2024Article
- Assessment of Passive Upper Limb Stiffness and Its Function in Post-Stroke Individuals Wearing an Inertial Sensor during the Pendulum Test.Sensors (Basel, Switzerland) · 2023Article
- Reference Values of the Forearm Tremor Power Spectra for Youth Athletes.Journal of human kinetics · 2023Article
- The Influence of Fatigue on the Characteristics of Physiological Tremor and Hoffmann Reflex in Young Men.International journal of environmental research and public health · 2023Article
- Mental calculation increases physiological postural tremor, but does not influence physiological goal-directed kinetic tremor.European journal of applied physiology · 2022Article
- Parkinson's Disease Exhibits Amplified Intermuscular Coherence During Dynamic Voluntary Action.Frontiers in neurology · 2020Article
- Voluntary and tremorogenic inputs to motor neuron pools of agonist/antagonist muscles in essential tremor patients.Journal of neurophysiology · 2019Article
- Muscle thixotropy-where are we now?Journal of applied physiology (Bethesda, Md. : 1985) · 2019Review
- Analyses of physiological wrist tremor with increased muscle activity during bench press exercise.Journal of exercise nutrition & biochemistry · 2019Article
- Hands train the brain-what is the role of hand tremor and anxiety in undergraduate microsurgical skills?Acta neurochirurgica · 2018Article
- Characteristics of Rest and Postural Tremors in Parkinson's Disease: An Analysis of Motor Unit Firing Synchrony and Patterns.Frontiers in human neuroscience · 2018Article
- Cardinal features of involuntary force variability can arise from the closed-loop control of viscoelastic afferented muscles.PLoS computational biology · 2018Article
- Fundamental Principles of Tremor Propagation in the Upper Limb.Annals of biomedical engineering · 2017Article
- Physiological tremor reveals how thixotropy adapts skeletal muscle for posture and movement.Royal Society open science · 2016Article
- The Dynamics of Voluntary Force Production in Afferented Muscle Influence Involuntary Tremor.Frontiers in computational neuroscience · 2016Article
- Increased gravitational force reveals the mechanical, resonant nature of physiological tremor.The Journal of physiology · 2015Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limb resonance imparts a characteristic spectrum to hand tremor. Movement will alter the resonance. We have examined the consequences of this change. Rectified forearm extensor muscle EMG and physiological hand tremor were recorded. In postural conditions the EMG spectrum is relatively flat whereas the acceleration spectrum is sharply peaked. Consequently, the gain between EMG and acceleration is maximal at the frequency where the tremor is largest (∼8 Hz). The shape of the gain curve implies mechanical resonance. Substantial alterations in posture do not significantly change the characteristics of the tremor or the shape or size of the gain curve. By contrast, slow or moderately paced voluntary wrist flexion–extension movements dramatically increase the hand tremor size and lower its peak frequency. These changes in size and frequency of the tremor cannot be attributed to changes in the EMG. Instead they reflect a very large change in the size and shape of the gain curve relating EMG to acceleration. The gain becomes larger and the peak moves to a lower frequency (∼6 Hz). We suggest that a movement-related (thixotropic) alteration in resonant properties of the wrist provides a simple explanation for these changes. The mechanism is illustrated by a model. Our new findings confirm that resonance plays a major role in wrist tremor. We also demonstrate that muscles operate very differently under postural and dynamic conditions. The different coupling between EMG and movement in posture and when moving must pose a considerable challenge for neural predictive control of skeletal muscles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.