Evidence map›Paper›PMID 22431266›Full record

ReviewAutism research : official journal of the International Society for Autism Research2012

Male gender bias in autism and pediatric autoimmunity.

Kevin G Becker

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Autism research : official journal of the International Society for Autism Research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02746445 completednot on this mapstarted 2016, after this paper: background citation

A Longitudinal Study on the Safety and Efficacy for Subjects With Autism Spectrum Disorder (ASD) Who Received Magnetic EEG/ECG-Guided Resonance Therapy (MeRT)

TypeobservationalSponsorWave NeuroscienceRan2016 to 2017Enrolled11ConditionsAutistic DisorderArmsNo intervention
NCT02758496 completednot on this mapstarted 2016, after this paper: background citation

A Chart Review to Evaluate the Safety and Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on Subjects With Autism Spectrum Disorder (ASD)

TypeobservationalSponsorWave NeuroscienceRan2016 to 2017Enrolled141ConditionsAutistic DisorderArmsMeRT Efficacy Chart Review
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kevin G BeckerGene Expression and Genomics Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. beckerk@grc.nia.nih.gov

Funding

Bioinformatic Analysis of the Genetics of Common Complex DiseasesZICAG000613 · NIA · NATIONAL INSTITUTE ON AGING · PI DE, SUPRIYO · 2010 to 2025
$3.1M
Intramural NIH HHS ZIC AG000613
6 · The paper itself

Abstract

Male bias in both autism and pediatric autoimmune disease is thought to involve hormonal perturbations in pregnancy or early childhood in the context of genetic control. These early molecular events, at a time of rapid development, are intimately linked to concurrent development in the brain and immune system. It is suggested here that these early regulatory events may overlap between autism and autoimmunity in determining male sex bias and may provide evidence of an etiological link among autism, immune dysregulation, and autoimmune disease.

Indexed as

Autistic DisorderAutoimmune DiseasesCentral Nervous SystemChildChild Development Disorders, PervasiveFemaleGenetic Diseases, X-LinkedGenetic Predisposition to DiseaseHumansMaleSex RatioTestosteroneTestosterone

Identifiers

PMID22431266
PMCPMC4530611

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.