ArticleIrish journal of medical science2012
The natural history of injecting drug use: a 25-year longitudinal study of a cohort of injecting drug users in inner city Dublin.
Article in Irish journal of medical science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Hepatitis C virus infection in Irish drug users and prisoners - a scoping review.BMC infectious diseases · 2019Article
- Twenty years of the methadone treatment protocol in Ireland: reflections on the role of general practice.Harm reduction journal · 2019Review
- Primary care and youth mental health in Ireland: qualitative study in deprived urban areas.BMC family practice · 2013Article
- Mortality in a large community-based cohort of inner-city residents in Vancouver, Canada.CMAJ open · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
backgroundInjecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland.
aimTo establish the natural history of IDUs in a deprived Dublin community.
methodsEighty-two IDUs (heroin) were recruited over the summer months of 1985. The prevalence of drug use in this district electoral area was established in 1985 and followed-up over a 25-year period with two formal interviews in 1995 and 2010.
resultsIt is a descriptive study of a cohort of IDUs established in 1985 prior to human immunodeficiency virus (HIV) testing being available. The majority of the cohort recruited included single, unemployed males aged 20 to 29 years, who had served a prison sentence. Fifty-one (63 %) of the cohort had died by 2010, of which 26 were attributed to HIV disease. The mean age of death was 35.9 years of age (standard deviation 4.1 years). Fifty-two (63 %) of the cohort tested positive for HIV and 58 (71 %) for hepatitis B between 1985 and 2010. The median survival time for those with a positive HIV status was 17 years (95 % CI 14.0-20.0) and for those with a positive hepatitis C status, 21 years (95 % CI 15.5-26.5).
conclusionsThe lifestyle of IDUs, as demonstrated by the experience of this cohort, has hazardous consequences resulting in high levels of morbidity and mortality. A relatively stable picture of HIV associated with IDUs is now emerging in Ireland, as is the case throughout most of the EU. HIV is a more manageable chronic disease, posing challenges for primary care in its treatment of former and existing IDUs who are ageing and now have other chronic diseases.
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