ArticleEvoDevo2012
Developmental diversity in free-living flatworms.
Article in EvoDevo, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
28 citing papers in PubMed, 93 citations in OpenAlex.
- Recent postglacial population expansions may explain a surprising lack of lineage splitting in Arctic meiobenthic flatworms.BMC ecology and evolution · 2026Article
- βcatenin-1 localization and transcriptomic profiling provide insights into the early development of planarians.BMC biology · 2025Article
- The Ultrastructure of the Apical Organ of the Goette's Larvae of the Polyclad Flatworm Stylochus pilidium Indicates Homology Between Polyclad Larvae.Cell biology international · 2025Article
- Flatworm cocoons in the abyss: same plan under pressure.Biology letters · 2024Article
- The evolution of gastrulation morphologies.Development (Cambridge, England) · 2023Review
- A phylogenomic approach to resolving interrelationships of polyclad flatworms, with implications for life-history evolution.Royal Society open science · 2023Article
- A Krüppel-like factor is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians.PLoS biology · 2022Article
- Three in one: evolution of viviparity, coenocytic placenta and polyembryony in cyclostome bryozoans.BMC ecology and evolution · 2021Article
- Regeneration of the flatworm Prosthiostomum siphunculus (Polycladida, Platyhelminthes).Cell and tissue research · 2021Article
- A global metabarcoding analysis expands molecular diversity of Platyhelminthes and reveals novel early-branching clades.Biology letters · 2019Article
- Reinvestigating the early embryogenesis in the flatwormEvoDevo · 2019Article
- Role of neoblasts in the patterned postembryonic growth of the platyhelminthNeurogenesis (Austin, Tex.) · 2018Article
- Genome-wide transcriptome profiling and spatial expression analyses identify signals and switches of development in tapeworms.EvoDevo · 2018Article
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- Article
- Embryonic chirality and the evolution of spiralian left-right asymmetries.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Identification of new markers for the Schistosoma mansoni vitelline lineage.International journal for parasitology · 2016Article
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- Comparative analysis of Wnt expression identifies a highly conserved developmental transition in flatworms.BMC biology · 2016Article
- A transcriptomic-phylogenomic analysis of the evolutionary relationships of flatworms.Current biology : CB · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 4 countries.
Funding
Abstract
Flatworm embryology has attracted attention since the early beginnings of comparative evolutionary biology. Considered for a long time the most basal bilaterians, the Platyhelminthes (excluding Acoelomorpha) are now robustly placed within the Spiralia. Despite having lost their relevance to explain the transition from radially to bilaterally symmetrical animals, the study of flatworm embryology is still of great importance to understand the diversification of bilaterians and of developmental mechanisms. Flatworms are acoelomate organisms generally with a simple centralized nervous system, a blind gut, and lacking a circulatory organ, a skeleton and a respiratory system other than the epidermis. Regeneration and asexual reproduction, based on a totipotent neoblast stem cell system, are broadly present among different groups of flatworms. While some more basally branching groups - such as polyclad flatworms - retain the ancestral quartet spiral cleavage pattern, most flatworms have significantly diverged from this pattern and exhibit unique strategies to specify the common adult body plan. Most free-living flatworms (i.e. Platyhelminthes excluding the parasitic Neodermata) are directly developing, whereas in polyclads, also indirect developers with an intermediate free-living larval stage and subsequent metamorphosis are found. A comparative study of developmental diversity may help understanding major questions in evolutionary biology, such as the evolution of cleavage patterns, gastrulation and axial specification, the evolution of larval types, and the diversification and specialization of organ systems. In this review, we present a thorough overview of the embryonic development of the different groups of free-living (turbellarian) platyhelminths, including the Catenulida, Macrostomorpha, Polycladida, Lecithoepitheliata, Proseriata, Bothrioplanida, Rhabdocoela, Fecampiida, Prolecithophora and Tricladida, and discuss their main features under a consensus phylogeny of the phylum.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.