ArticleBMC research notes2012
Prevalence of Coxiella burnetii in clinically healthy German sheep flocks.
Article in BMC research notes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Prevalence and risk factors of neglected zoonoses in Ethiopian small ruminants: a focus on Q fever, brucellosis, chlamydiosis, and toxoplasmosis.One health outlook · 2026Article
- Serological evidence of Q fever in Tibetan sheep in Qinghai Province, China.One health (Amsterdam, Netherlands) · 2025Article
- Molecular detection and phylogeny analysis ofNew microbes and new infections · 2024Article
- Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania.Scientific reports · 2022Article
- Impact ofFrontiers in veterinary science · 2022Article
- Q fever expertise among human and veterinary health professionals in Germany - A stakeholder analysis of knowledge gaps.PloS one · 2022Article
- Concept of an Active Surveillance System for Q Fever in German Small Ruminants-Conflicts Between Best Practices and Feasibility.Frontiers in veterinary science · 2021Article
- Evaluation of the Diagnostic Potential of RecombinantMicroorganisms · 2020Article
- Q fever: Evidence of a massive yet undetected cross-border outbreak, with ongoing risk of extra mortality, in a Dutch-German border region.Transboundary and emerging diseases · 2020Article
- Prevalence ofEpidemiology and infection · 2020Article
- Who is at risk of occupational Q fever: new insights from a multi-profession cross-sectional study.BMJ open · 2020Article
- Estimation of the frequency of Q fever in sheep, goat and cattle herds in France: results of a 3-year study of the seroprevalence of Q fever and excretion level of Coxiella burnetii in abortive episodes.Epidemiology and infection · 2017Article
- Article
- DNA microarray-based detection of Coxiella burnetii, the causative agent of Q fever.Acta veterinaria Scandinavica · 2014Article
- Coxiella burnetii - Pathogenic Agent of Q (Query) Fever.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent epidemiological data on the situation of Coxiella (C.) burnetii infections in sheep are missing, making risk assessment and the implementation of counteractive measures difficult. Using the German state of Thuringia as a model example, the estimated sero-, and antigen prevalence of C. burnetii (10% and 25%, respectively) was assessed at flock level in 39/252 randomly selected clinically healthy sheep flocks with more than 100 ewes and unknown abortion rate.
resultsThe CHECKIT™ Q-fever Test Kit identified 11 (28%) antibody positive herds, whereas real-time PCR revealed the presence of C. burnetii DNA in 2 (5%) of the flocks. Multiple-locus variable number of tandem repeats analysis of 9 isolates obtained from one flock revealed identical profiles. All isolates contained the plasmid QpH1.
conclusionsThe results demonstrate that C. burnetii is present in clinically inconspicuous sheep flocks and sporadic flare-ups do occur as the notifications to the German animal disease reporting system show. Although C. burnetii infections are not a primary veterinary concern due to the lack of significant clinical impact on animal health (with the exception of goats), the eminent zoonotic risk for humans should not be underestimated. Therefore, strategies combining the interests of public and veterinary public health should include monitoring of flocks, the identification and culling of shedders as well as the administration of protective vaccines.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.