Evidence map›Paper›PMID 22429090›Full record

ArticleJournal of medical primatology2012

Lactobacillus and Pediococcus species richness and relative abundance in the vagina of rhesus monkeys (Macaca mulatta).

Michael G Gravett, Ling Jin, Sylvia I Pavlova, Lin Tao

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical primatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael G GravettDepartment of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA.
Ling Jin
Sylvia I Pavlova
Lin Tao
University of Illinois Chicago · USOregon National Primate Research Center · US

Funding

Lactobacilli: Blocking HIV/HSV by Mannose BindingU01AI066709 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TAO, LIN · 2005 to 2009
$2.5M
EXPERIMENTAL MODEL FOR CHORIOAMNIONITIS AND PREMATURITYR01AI042490 · NIAID · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI GRAVETT, MICHAEL G · 1997 to 2005
$1.4M
Viral Infection in Lactobacilli: An Animal BV ModelR21AI054655 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TAO, LIN · 2003 to 2004
$468k
NIAID NIH HHS AI042490NIAID NIH HHS AI054655NIAID NIH HHS AI066709NIAID NIH HHS R01 AI042490NIAID NIH HHS R21 AI054655NIAID NIH HHS U01 AI066709
6 · The paper itself

Abstract

backgroundThe rhesus monkey is an important animal model to study human vaginal health to which lactic acid bacteria play a significant role. However, the vaginal lactic acid bacterial species richness and relative abundance in rhesus monkeys is largely unknown.

methodsVaginal swab samples were aseptically obtained from 200 reproductive-aged female rhesus monkeys. Following Rogosa agar plating, single bacterial colonies representing different morphotypes were isolated and analyzed for whole-cell protein profile, species-specific polymerase chain reaction, and 16S rRNA gene sequence.

resultsA total of 510 Lactobacillus strains of 17 species and one Pediococcus acidilactici were identified. The most abundant species was Lactobacillus reuteri, which colonized the vaginas of 86% monkeys. Lactobacillus johnsonii was the second most abundant species, which colonized 36% of monkeys. The majority of monkeys were colonized by multiple Lactobacillus species.

conclusionsThe vaginas of rhesus monkeys are frequently colonized by multiple Lactobacillus species, dominated by L. reuteri.

Indexed as

AnimalsFemaleLactobacillusMacaca mulattaPediococcusPhylogenyPolymerase Chain ReactionRNA, BacterialRNA, Ribosomal, 16SSpecies SpecificityVaginaRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID22429090
PMCPMC3360820
OpenAlexW1563536978

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.