ArticlePloS one2012
A novel betaproteobacterial agent of gill epitheliocystis in seawater farmed Atlantic salmon (Salmo salar).
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- From onset to healing: temporal dynamics of microbial communities pinpoint Midichloria-like organism's key role in the development of the fish skin disease red mark syndrome.Animal microbiome · 2026Article
- Association of microbial community structure with gill disease in marine-stage farmed Atlantic salmon (Salmo salar); a yearlong study.BMC veterinary research · 2024Article
- Effectiveness of functional ingredients to enhance gill disease in Atlantic salmon (Salmo salar, L.).PloS one · 2024Article
- The Fish Pathogen "Candidatus Clavichlamydia salmonicola"-A Missing Link in the Evolution of Chlamydial Pathogens of Humans.Genome biology and evolution · 2023Article
- Phylogenetic analyses of Candidatus Branchiomonas cysticola refine the taxonomic classification of Betaproteobacteria associated with epitheliocystis in fish.Archives of microbiology · 2023Article
- Infectious agents and their physiological correlates in early marine Chinook salmon (Conservation physiology · 2023Article
- A cohort study of gill infections, gill pathology and gill-related mortality in sea-farmed Atlantic salmon (Salmo salar L.): A descriptive analysis.Journal of fish diseases · 2022Article
- Prospective Longitudinal Study of Putative Agents Involved in Complex Gill Disorder in Atlantic salmon (Pathogens (Basel, Switzerland) · 2022Article
- Identification of housekeeping genes of Candidatus Branchiomonas cysticola associated with epitheliocystis in Atlantic salmon (Salmo salar L.).Archives of microbiology · 2022Article
- Expansion of the Beta-Proteobacterial GenusPathogens (Basel, Switzerland) · 2022Article
- Epitheliocystis in Greater Amberjack: Evidence of a Novel Causative Agent, Pathology, Immune Response and Epidemiological Findings.Microorganisms · 2022Article
- Multi-agentFish and shellfish immunology reports · 2021Article
- Effects of ploidy and salmonid alphavirus infection on the skin and gill microbiome of Atlantic salmon (Salmo salar).PloS one · 2021Article
- Draft Genome Sequences ofMicrobiology resource announcements · 2020Article
- Comparison of histologic methods for the detection ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020Article
- Analysis of the gut and gill microbiome of resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss).Fish & shellfish immunology · 2019Article
- Comparison of infectious agents detected from hatchery and wild juvenile Coho salmon in British Columbia, 2008-2018.PloS one · 2019Article
- Evidence of a hydraulically challenging reach serving as a barrier for the upstream migration of infection-burdened adult steelhead.Conservation physiology · 2019Article
- Histopathological investigation of complex gill disease in sea farmed Atlantic salmon.PloS one · 2019Article
- Intracellular Bacterial Infections: A Challenge for Developing Cellular Mediated Immunity Vaccines for Farmed Fish.Microorganisms · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epitheliocystis, a disease characterised by cytoplasmic bacterial inclusions (cysts) in the gill and less commonly skin epithelial cells, has been reported in many marine and freshwater fish species and may be associated with mortality. Previously, molecular and ultrastructural analyses have exclusively associated members of the Chlamydiae with such inclusions. Here we investigated a population of farmed Atlantic salmon from the west coast of Norway displaying gill epitheliocystis. Although 'Candidatus Piscichlamydia salmonis', previously reported to be present in such cysts, was detected by PCR in most of the gill samples analysed, this bacterium was found to be a rare member of the gill microbiota, and not associated with the observed cysts as demonstrated by fluorescence in situ hybridization assays. The application of a broad range 16 S rRNA targeted PCR assay instead identified a novel betaproteobacterium as an abundant member of the gill microbiota. Fluorescence in situ hybridization demonstrated that this bacterium, tentatively classified as 'Candidatus Branchiomonas cysticola', was the cyst-forming agent in these samples. While histology and ultrastructure of 'Ca. B. cysticola' cysts revealed forms similar to the reticulate and intermediate bodies described in earlier reports from salmon in seawater, no elementary bodies typical of the chlamydial developmental cycle were observed. In conclusion, this study identified a novel agent of epitheliocystis in sea-farmed Atlantic salmon and demonstrated that these cysts can be caused by bacteria phylogenetically distinct from the Chlamydiae.
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