ArticlePLoS medicine2012
Uterine rupture by intended mode of delivery in the UK: a national case-control study.
Article in PLoS medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 4 of them syntheses that pooled it.
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Who cites it
74 citing papers in PubMed, 4 syntheses or guidelines pooled it, 219 citations in OpenAlex.
- Trial of Labor After Cesarean and Vaginal Birth After Cesarean: A Systematic Review and Meta-Analysis of Maternal and Neonatal Outcomes.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Pooled it
- Prevalence and determinants of uterine rupture in Ethiopia: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Prevalence and predictors of uterine rupture among Ethiopian women: A systematic review and meta-analysis.PloS one · 2020Pooled it
- OptiBIRTH: a cluster randomised trial of a complex intervention to increase vaginal birth after caesarean section.BMC pregnancy and childbirth · 2020Trial
- Caesarean section surgical techniques: 3 year follow-up of the CORONIS fractional, factorial, unmasked, randomised controlled trial.Lancet (London, England) · 2016Trial
- Trial
- Article
- Spontaneous posterior uterine rupture following vaginal delivery in an unscarred uterus.BMJ case reports · 2026Article
- Article
- Use of evidence from the UK Obstetric Surveillance System in policy and clinical practice: a descriptive study using citation tracking.NIHR open research · 2026Article
- Analysis of the uterine rupture during pregnancy and delivery in a provincial maternal and children care hospital in China: 2013-2022.BMC pregnancy and childbirth · 2025Article
- Risk factors for complete uterine rupture in patients with trial of labor after cesarean delivery.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Inter-pregnancy interval and uterine rupture during a trial of labour after one previous caesarean delivery and no previous vaginal births: a retrospective population-based cohort study.EClinicalMedicine · 2025Article
- The possible impact of the universal two-child policy on pregnancy outcomes.Archives of gynecology and obstetrics · 2024Article
- How the Mode of Delivery Is Influenced by Patient's Opinions and Risk-Informed Consent in Women with a History of Caesarean Section? Is Vaginal Delivery a Real Option after Caesarean Section?Journal of clinical medicine · 2024Article
- [Retrospective study of 60 cases of uterine rupture at the Maternity Center of Monastir, Tunisia].The Pan African medical journal · 2024Article
- Delivery Progress, Labor Interventions and Perinatal Outcome in Spontaneous Vaginal Delivery of Singleton Pregnancies between Nulliparous and Primiparous Women with One Previous Elective Cesarean Section: A Retrospective Comparative Study.Life (Basel, Switzerland) · 2023Article
- Uterine rupture and factors associated with adverse outcomes.Archives of gynecology and obstetrics · 2023Article
- Induction of Labor in Women with Previous Cesarean Section and Unfavorable Cervix: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2023Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent reports of the risk of morbidity due to uterine rupture are thought to have contributed in some countries to a decrease in the number of women attempting a vaginal birth after caesarean section. The aims of this study were to estimate the incidence of true uterine rupture in the UK and to investigate and quantify the associated risk factors and outcomes, on the basis of intended mode of delivery. METHODS AND
findingsA UK national case-control study was undertaken between April 2009 and April 2010. The participants comprised 159 women with uterine rupture and 448 control women with a previous caesarean delivery. The estimated incidence of uterine rupture was 0.2 per 1,000 maternities overall; 2.1 and 0.3 per 1,000 maternities in women with a previous caesarean delivery planning vaginal or elective caesarean delivery, respectively. Amongst women with a previous caesarean delivery, odds of rupture were also increased in women who had ≥ two previous caesarean deliveries (adjusted odds ratio [aOR] 3.02, 95% CI 1.16-7.85) and <12 months since their last caesarean delivery (aOR 3.12, 95% CI 1.62-6.02). A higher risk of rupture with labour induction and oxytocin use was apparent (aOR 3.92, 95% CI 1.00-15.33). Two women with uterine rupture died (case fatality 1.3%, 95% CI 0.2-4.5%). There were 18 perinatal deaths associated with uterine rupture among 145 infants (perinatal mortality 124 per 1,000 total births, 95% CI 75-189).
conclusionsAlthough uterine rupture is associated with significant mortality and morbidity, even amongst women with a previous caesarean section planning a vaginal delivery, it is a rare occurrence. For women with a previous caesarean section, risk of uterine rupture increases with number of previous caesarean deliveries, a short interval since the last caesarean section, and labour induction and/or augmentation. These factors should be considered when counselling and managing the labour of women with a previous caesarean section.
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