ArticleThe Journal of infectious diseases2012
Association between gastric Helicobacter pylori colonization and glycated hemoglobin levels.
Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Pooled it
- Helicobacter pylori infection as a risk factor for diabetes: a meta-analysis of case-control studies.BMC gastroenterology · 2020Pooled it
- Is Helicobacter pylori infection associated with glycemic control in diabetics?World journal of gastroenterology · 2015Pooled it
- Male non-insulin users with type 2 diabetes mellitus are predisposed to gastric corpus-predominant inflammation after H. pylori infection.Journal of biomedical science · 2017Trial
- Association betweenThe Journal of international medical research · 2026Article
- Helicobacter pylori seroprevalence and its association with prevalent and incident blood pressure and haemoglobin A1c in the US-based National Longitudinal Study of Adolescent to Adult Health.BMJ public health · 2026Article
- Association between triglyceride-glucose index andFrontiers in endocrinology · 2025Article
- Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents.BMC medicine · 2024Article
- Association between Helicobacter pylori infection and type 2 diabetes mellitus: a retrospective cohort study and bioinformatics analysis.BMC endocrine disorders · 2024Article
- A laboratory-based cross-sectional study about helicobacter pylori infection and diabetes.Caspian journal of internal medicine · 2024Article
- Relationship betweenFrontiers in cellular and infection microbiology · 2023Article
- Bone Fragility in Gastrointestinal Disorders.International journal of molecular sciences · 2022Review
- Helicobacter pylori infection is not an independent risk factor of non-alcoholic fatty liver disease in China.BMC gastroenterology · 2022Article
- Factors associated with gastro-duodenal ulcer in compensated type 2 diabetic patients: a Romanian single-center study.Archives of medical science : AMS · 2022Article
- Increased Glycated Hemoglobin but Decreased Cholesterol after a Loss ofJournal of personalized medicine · 2021Article
- Helicobacter pylori infection causes both protective and deleterious effects in human health and disease.Genes and immunity · 2021Review
- Article
- Differences in glycated hemoglobin levels and cholesterol levels in individuals with diabetes according to Helicobacter pylori infection.Scientific reports · 2021Article
- Helicobacter pylori infection, a risk factor for Type 2 diabetes mellitus: a hospital-based cross-sectional study among dyspeptic patients in Douala-Cameroon.Scientific reports · 2020Article
- Increased Glycated Hemoglobin Levels in Patients WithFrontiers in immunology · 2020Article
Corrections and comments
- Commented on by
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundFew studies have evaluated the potential influence of Helicobacter pylori on biomarkers for diabetes.
methodsWe conducted cross-sectional analyses using data from 7417 participants in the National Health and Nutrition Examination Survey (NHANES) III (aged ≥18 years) and 6072 participants in NHANES 1999-2000 (aged ≥3 years) to assess the association between H. pylori and levels of glycosylated hemoglobin (HbA1c).
resultsThere was no association between H. pylori and history of self-reported diabetes. Helicobacter pylori seropositivity, especially H. pylori cagA positivity, was positively associated (P < .01, NHANES III; P = .02, NHANES 1999-2000) with HbA1c levels after excluding individuals with history of diabetes and controlling for potential confounders. There was also a synergistic interaction between H. pylori and higher body mass index (BMI), such that increased levels of HbA1c associated with having both H. pylori and higher BMI were greater than the sum of their individual effects (P for interaction < .01). This interaction was observed consistently in both NHANES III and NHANES 1999-2000 and for H. pylori cagA positivity in NHANES III.
conclusionsThe findings indicate a role of H. pylori in impaired glucose tolerance in adults that may be potentiated by higher BMI level.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.