ArticleThe Journal of biological chemistry2012
Formation of dAMP-glycerol and dAMP-Tris derivatives by Thermococcus kodakaraensis DNA primase.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- A primase subunit essential for efficient primer synthesis by an archaeal eukaryotic-type primase.Nature communications · 2015Article
- A highly divergent archaeo-eukaryotic primase from the Thermococcus nautilus plasmid, pTN2.Nucleic acids research · 2014Article
- RecJ-like protein from Pyrococcus furiosus has 3'-5' exonuclease activity on RNA: implications for proofreading of 3'-mismatched RNA primers in DNA replication.Nucleic acids research · 2013Article
- Characterization of DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis.The Journal of biological chemistry · 2012Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
In the presence of dATP, glycerol, and Tris buffer, the DNA primase isolated from Thermococcus kodakaraensis catalyzed the formation of dAMP and two products that were identified as dAMP-glycerol and dAMP-Tris. These products were formed by the T. kodakaraensis p41 catalytic subunit alone and the T. kodakaraensis p41-p46 complex in the absence of a DNA template. They were not formed with preparations containing the catalytically inactive p41 subunit. Similar glycerol and Tris derivatives as well as dNMPs were also formed with dGTP, dCTP, or dTTP. The mechanism contributing to the formation of these products and its implications in the initiation reaction catalyzed by the T. kodakaraensis primase are discussed.
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