ArticleInvestigative ophthalmology & visual science2012
Increased mortality risk among the visually impaired: the roles of mental well-being and preventive care practices.
Article in Investigative ophthalmology & visual science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Mediation analysis with a time-to-event outcome: a review of use and reporting in healthcare research.BMC medical research methodology · 2018Pooled it
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- Mobile Objective Diagnostics of Macular Degeneration using Dark-Adapted Visual Evoked Potentials.medRxiv : the preprint server for health sciences · 2025Article
- Agreement between CES-D and CIDI-SF scales of depression among older adults: a cross-sectional comparative study based on the longitudinal aging study in India, 2017-19.BMC psychiatry · 2025Article
- Self-Reported Visual Difficulty and Mortality Risk Among Older Adults: The Mediating Role of Recurrent Falls.Innovation in aging · 2025Article
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- Periodic health evaluation in Para athletes: a position statement based on expert consensus.BMJ open sport & exercise medicine · 2024Article
- A Population-Based Cohort Study of the Association between Visual Loss and Risk of Suicide and Mental Illness in Taiwan.Healthcare (Basel, Switzerland) · 2023Article
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- Near Vision but not Hearing Loss is Associated with Lacking a Usual Source of Health Care.Journal of aging and health · 2021Article
- Visual impairment and ten-year mortality: the Liwan Eye Study.Eye (London, England) · 2021Article
- Portable Diagnostic System for Age-Related Macular Degeneration Screening Using Visual Evoked Potentials.Eye and brain · 2021Article
- Comparison of Visual Acuity Measurement Using Three Methods: Standard ETDRS Chart, Near Chart and a Smartphone-Based Eye Chart Application.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Modification of the Association between Visual Impairment and Mortality by Physical Activity: A Cohort Study among the Korean National Health Examinees.International journal of environmental research and public health · 2019Article
- Development and Validation of a Smartphone-Based Visual Acuity Test (Vision at Home).Translational vision science & technology · 2019Article
- Association of Visual Impairment and All-Cause 10-Year Mortality Among Indigenous Australian Individuals Within Central Australia: The Central Australian Ocular Health Study.JAMA ophthalmology · 2018Article
- The Association of Visual Impairment With Clinical Outcomes in Hemodialysis Patients.Medicine · 2016Article
- Visual Function in Older Eyes in Normal Macular Health: Association with Incident Early Age-Related Macular Degeneration 3 Years Later.Investigative ophthalmology & visual science · 2016Article
- A conceptual model for vision rehabilitation.Journal of rehabilitation research and development · 2016Review
- Eye Care Quality and Accessibility Improvement in the Community (EQUALITY) for adults at risk for glaucoma: study rationale and design.International journal for equity in health · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeMechanisms by which visual impairment (VI) increases mortality risk are poorly understood. We estimated the direct and indirect effects of self-rated VI on risk of mortality through mental well-being and preventive care practice mechanisms.
methodsUsing complete data from 12,987 adult participants of the 2000 Medical Expenditure Panel Survey with mortality linkage through 2006, we undertook structural equation modeling using two latent variables representing mental well-being and poor preventive care to examine multiple effect pathways of self-rated VI on all-cause mortality. Generalized linear structural equation modeling was used to simultaneously estimate pathways including the latent variables and Cox regression model, with adjustment for controls and the complex sample survey design.
resultsVI increased the risk of mortality directly after adjusting for mental well-being and other covariates (hazard ratio [HR] = 1.25 [95% confidence interval: 1.01, 1.55]). Poor preventive care practices were unrelated to VI and to mortality. Mental well-being decreased mortality risk (HR = 0.68 [0.64, 0.74], P < 0.001). VI adversely affected mental well-being (β = -0.54 [-0.65, -0.43]; P < 0.001). VI also increased mortality risk indirectly through mental well-being (HR = 1.23 [1.16, 1.30]). The total effect of VI on mortality including its influence through mental well-being was HR 1.53 [1.24, 1.90]. Similar but slightly stronger patterns of association were found when examining cardiovascular disease-related mortality, but not cancer-related mortality.
conclusionsVI increases the risk of mortality directly and indirectly through its adverse impact on mental well-being. Prevention of disabling ocular conditions remains a public health priority along with more aggressive diagnosis and treatment of depression and other mental health conditions in those living with VI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.