ArticleDigestive diseases and sciences2012
Variables associated with stress ulcer prophylaxis misuse: a retrospective analysis.
Article in Digestive diseases and sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Evaluation of Stress Ulcer Prophylaxis Use Among Adult Patients Admitted to the Intensive Care Unit in Northwest Ethiopia Hospitals During 2024: A Multicenter Cross-Sectional Study.Health science reports · 2026Article
- Appropriateness of stress ulcer prophylaxis and associated factors among patients in medical, surgical, and intensive care units at Wolaita Sodo university comprehensive specialized hospital, Ethiopia: a cross-sectional study.BMC gastroenterology · 2026Article
- Optimizing stress ulcer prophylaxis practices and reducing associated costs in intensive care units: a non-randomized controlled study.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025Article
- Ensuring guideline adherence and cost savings in stress ulcer prophylaxis practices in the intensive care unit: a pre-post education study.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025Article
- Analysis of inappropriate prophylactic use of proton pump inhibitors during the perioperative period: an observational study.Perioperative medicine (London, England) · 2024Article
- A case of pancreaticoduodenal artery bleeding after laparoscopic right colectomy requiring open hemostasis.Surgical case reports · 2024Article
- Assessment of the appropriateness of stress ulcer prophylaxis use and its determinants among admitted surgical patients at Debre Berhan University Hakim Gizaw Hospital, Ethiopia. A hospital-based cross-sectional study.Frontiers in medicine · 2024Article
- Appropriateness and Associated Factors of Stress Ulcer Prophylaxis for Surgical Inpatients of Orthopedics Department in a Tertiary Hospital: A Cross-Sectional Study.Frontiers in pharmacology · 2022Article
- Adherence to a stress ulcer prophylaxis protocol by critically ill patients: a prospective cohort study.Revista Brasileira de terapia intensiva · 2020Article
- Assessment of pharmacologic prophylaxis use against stress ulcer in the medical wards of University of Gondar Hospital.SAGE open medicine · 2019Article
- Variables Associated with Adherence to Stress Ulcer Prophylaxis in Patients Admitted to the General Hospital Wards: A Prospective Study.Advanced pharmaceutical bulletin · 2017Article
- The Italian Society of Internal Medicine choosing wisely campaign.Internal and emergency medicine · 2016Article
- Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression.BMC medicine · 2016Review
- Identifying Risk Factors Associated with Inappropriate Use of Acid Suppressive Therapy at a Community Hospital.Gastroenterology research and practice · 2016Article
- Use of proton pump inhibitors for the provision of stress ulcer prophylaxis: clinical and economic consequences.PharmacoEconomics · 2014Review
- Stress ulcer prophylaxis, thromboprophylaxis and coagulation management in patients with hip fractures.Wiener medizinische Wochenschrift (1946) · 2013Review
- Adherence to stress-related mucosal damage prophylaxis guideline in patients admitted to the Intensive Care Unit.Journal of research in pharmacy practiceArticle
- Attachment to stress ulcer prophylaxis guideline in the neurology wards of two teaching and non-teaching hospitals: A retrospective survey in Iran.Journal of research in pharmacy practiceArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStress ulcer prophylaxis (SUP) is commonly used in hospitals. Although its indications are better delineated for intensive care unit (ICU) patients, its use in non-ICU settings is somewhat arbitrary and based on judgment.
objectiveWe attempted to assess the extent of SUP overuse in our hospital. We also carefully collected and analyzed several variables to detect associations governing this flawed behavior and its financial burden on the hospital's budget. MATERIALS AND
methodsWe retrospectively analyzed charts of patients admitted to the medical floor of a tertiary referral university hospital over a 1 year period. All adult patients admitted to the medical ward who received at least one dose of SUP were included and reviewed for a multitude of variables in addition to the appropriateness of acid suppression therapy (AST).
resultsWe included 320 charts and found that 92% of patients admitted during that period were not eligible for SUP. The total inappropriateness of SUP was noted to be 58% (p = 0.015). Increasing age and male gender were found to be significant variables in AST misuse (p = 0.045 and p = 0.010), much like duration of hospital stay (p = 0.008). Comorbidities was also found to be a defining variable for AST overuse (odds ratio [OR] = 3.27). Patients with two or more minor risk factors were also subjected more to SUP inappropriately (OR = 3.53), in addition to patients of certain specialties (Neurology, Infectious Diseases, etc.). Our calculated financial burden was more than $23,000 per year for the medical floor.
conclusionThis retrospective study confirmed the growing suspicion that SUP misuse is evident on the medical floors. We also delineated several factors and variables associated with and affecting SUP overuse.
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