ArticleHeart failure reviews2012
Renal dysfunction in acute and chronic heart failure: prevalence, incidence and prognosis.
Article in Heart failure reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 100 citations in OpenAlex.
- Congestion and renal function in patients with chronic heart failure.ESC heart failure · 2026Article
- The Link between Alcohol Consumption and Kidney Injury.The American journal of pathology · 2026Review
- Imaging of Congestion in Cardio-renal Syndrome.Current heart failure reports · 2025Review
- Kidney function changes in acute heart failure: a practical approach to interpretation and management.Clinical kidney journal · 2023Review
- Renal dysfunction and outcome in left ventricular non-compaction.Cardiology journal · 2023Article
- Delayed Improvement of Left Ventricular Function in Newly Diagnosed Heart Failure Depends on Etiology-A PROLONG-II Substudy.Sensors (Basel, Switzerland) · 2022Article
- Advance Care Planning Documentation and Intensity of Care at the End of Life for Adults With Congestive Heart Failure, Chronic Kidney Disease, and Both Illnesses.Journal of pain and symptom management · 2022Article
- Prognostic Value of Pericardial Effusion Size in Patients with Acute Heart Failure.Current vascular pharmacology · 2022Article
- Different Renal Function Patterns in Patients With Acute Heart Failure: Relationship With Outcome and Congestion.Frontiers in cardiovascular medicine · 2022Article
- Renal dysfunction in cardiovascular diseases and its consequences.Journal of nephrology · 2021Review
- Systematic Review of the Association Between Worsening Renal Function and Mortality in Patients With Acute Decompensated Heart Failure.Kidney international reports · 2020Article
- Risk of end-stage renal disease in patients with hypertrophic cardiomyopathy: A nationwide population-based cohort study.Scientific reports · 2019Article
- Multimodality imaging for real-time image-guided left ventricular lead placement during cardiac resynchronization therapy implantations.The international journal of cardiovascular imaging · 2019Article
- Combined use of lung ultrasound, B-type natriuretic peptide, and echocardiography for outcome prediction in patients with acute HFrEF and HFpEF.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Article
- Erratum to: Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor.Clinical pharmacokinetics · 2018Article
- Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor.Clinical pharmacokinetics · 2017Review
- Impact of baseline renal function on all-cause mortality in patients who underwent cardiac resynchronization therapy: A systematic review and meta-analysis.Journal of arrhythmia · 2017Review
- Healthcare Costs for Acute Hospitalized and Chronic Heart Failure in South Korea: A Multi-Center Retrospective Cohort Study.Yonsei medical journal · 2017Observational
- Muscle mechanoreflex activation via passive calf stretch causes renal vasoconstriction in healthy humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- New challenges of geriatric cardiology: from clinical to preclinical research.Journal of geriatric cardiology : JGC · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most patients with heart failure have mild or moderate renal dysfunction. This reflects the combined impact of chronic renal parenchymal disease, renal artery disease, renal congestion and hypoperfusion, neuroendocrine and cytokine activation and the effects of treatments for heart failure. Remarkably, with good treatment, the average annual rate of decline in renal function is similar in patients with chronic heart failure and healthy people of a similar age. Urea appears to be a stronger marker of an adverse prognosis than creatinine-based measures of renal function. Recent evidence suggests that minor, transient increases in creatinine in the setting of acute heart failure are not prognostically important but persistent deterioration does indicate a higher mortality. The poor prognosis of patients with worsening renal function ensures that few require renal dialysis but this may change as methods to prevent sudden death improve and new ways are found to control fluid congestion. Reversing renal dysfunction and stopping its progression remain important targets for treatment of heart failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.