Evidence map›Paper›PMID 22425744›Full record

ReviewSeminars in cell & developmental biology2012

On the shoulders of giants: a historical perspective of unique experimental methods in mammary gland research.

Brittni A Smith, Alana L Welm, Bryan E Welm

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Brittni A SmithDepartment of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112 USA.
Alana L Welm
Bryan E Welm
University of Utah · USHuntsman Cancer Institute · US

Funding

Identification of Novel Cancer Selective Compounds in 3D Tumor Organoid AssaysR01CA140296 · NCI · UNIVERSITY OF UTAH · PI SIGMAN, MATTHEW S · 2009 to 2013
$1.5M
Analysis of the Cellular Origins of Breast CancerR01CA143815 · NCI · UNIVERSITY OF UTAH · PI WELM, BRYAN E. · 2010 to 2014
$1.5M
NCI NIH HHS R01 CA140296NCI NIH HHS R01CA140296NCI NIH HHS R01 CA143815NCI NIH HHS R01CA143815
6 · The paper itself

Abstract

While most organs undergo development in utero, the mouse mammary gland orchestrates five major developmental stages following birth: pre-puberty, puberty, pregnancy, lactation, and involution. Induced by both local and systemic factors, these five developmental stages transpire with dramatic alterations in glandular morphology and cellular function. As an experimental system, the mammary gland provides remarkable accessibility to processes regulating stem cell function, hormone response, and epithelial-stromal-extracellular matrix interactions. This review will provide a historical perspective of the unique in vitro and in vivo techniques used to study the mammary gland and how these methods have provided valuable insight into the biology of this organ.

Indexed as

Mammary Glands, AnimalAnimalsCloning, MolecularStem CellsStem Cell TransplantationTransgenes

Identifiers

PMID22425744
PMCPMC3398198
OpenAlexW1967099181

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.