Evidence map›Paper›PMID 22425576›Full record

ArticleSleep medicine2012

Risk factors for incident chronic insomnia: a general population prospective study.

Ravi Singareddy, Alexandros N Vgontzas, Julio Fernandez-Mendoza, Duanping Liao, Susan Calhoun, Michele L Shaffer, Edward O Bixler

Open access · bronzeAbstract read
In one paragraph

Article in Sleep medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 2 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 2 syntheses or guidelines pooled it, 268 citations in OpenAlex.

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  9. Sleep and obesity-known interactions and open questions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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  14. Obstructive sleep apnea comorbid with insomnia symptoms and objective short sleep duration is associated with incident hypertension.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ravi SingareddySleep Research & Treatment Center, Penn State University College of Medicine, Hershey, PA, United States. rsingareddy@hmc.psu.edu
Alexandros N Vgontzas
Julio Fernandez-Mendoza
Duanping Liao
Susan Calhoun
Michele L Shaffer
Edward O Bixler
Pennsylvania State University · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
PREVALENCE OF SLEEP DISORDERED BREATHING IN CHILDRENR01HL063772 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O. · 2001 to 2005
$1.3M
PREVALENCE OF SLEEP APNEA IN WOMENR01HL051931 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O. · 1994 to 1998
–
NCATS NIH HHS UL1 TR000127NHLBI NIH HHS R01 HL051931NHLBI NIH HHS R01 HL063772PHS HHS R01 40916PHS HHS R01 51931
6 · The paper itself

Abstract

objectiveThe few population-based, prospective studies that have examined risk factors of incident insomnia were limited by small sample size, short follow-up, and lack of data on medical disorders or polysomnography. We prospectively examined the associations between demographics, behavioral factors, psychiatric and medical disorders, and polysomnography with incident chronic insomnia.

methodsFrom a random, general population sample of 1741 individuals of the adult Penn State Sleep Cohort, 1395 were followed-up after 7.5 years. Only subjects without chronic insomnia at baseline (n = 1246) were included in this study. Structured medical and psychiatric history, personality testing, and 8-h polysomnography were obtained at baseline. Structured sleep history was obtained at baseline and follow-up.

resultsIncidence of chronic insomnia was 9.3%, with a higher incidence in women (12.9%) than in men (6.2%). Younger age (20-35 years), non-white ethnicity, and obesity increased the risk of chronic insomnia. Poor sleep and mental health were stronger predictors of incident chronic insomnia compared to physical health. Higher scores in MMPI-2, indicating maladaptive personality traits, and excessive use of coffee at baseline predicted incident chronic insomnia. Polysomnographic variables, such as short sleep duration or sleep apnea, did not predict incident chronic insomnia.

conclusionMental health, poor sleep, and obesity, but not sleep apnea, are significant risk factors for incident chronic insomnia. Focusing on these more vulnerable groups and addressing the modifiable risk factors may help reduce the incident of chronic insomnia, a common and chronic sleep disorder associated with significant medical and psychiatric morbidity and mortality.

Indexed as

AdultAgedAlcohol DrinkingCoffeeDepressionFemaleFollow-Up StudiesHumansIncidenceMaleMental HealthMiddle AgedMMPIMorbidityObesityPennsylvaniaCoffee

Identifiers

PMID22425576
PMCPMC3319648
OpenAlexW2171869503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.