Evidence map›Paper›PMID 22423895›Full record

ReviewBreast cancer research : BCR2012

Advances in molecular imaging for breast cancer detection and characterization.

Jennifer M Specht, David A Mankoff

Abstract readReview
In one paragraph

Review in Breast cancer research : BCR, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Frontiers in veterinary science · 2019
    Article
  4. Journal of biomedical science · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Positron Emission Tomography in Breast Cancer.Diagnostics (Basel, Switzerland) · 2015
    Review
  10. The role of general nuclear medicine in breast cancer.Journal of medical radiation sciences · 2015
    Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer M SpechtDivision of Medical Oncology, University of Washington, Seattle Cancer Care Alliance, 825 Eastlake Avenue East, G3-630, Seattle, WA 98109, USA. jspecht@uw.edu
David A Mankoff

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
RadiochemistryP01CA042045 · NCI · UNIVERSITY OF WASHINGTON · PI LINK, JEANNE MEYERS · 1986 to 2015
$23.2M
Targeted immunotherapy of breast cancer with central memory T cellsP50CA138293 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PORTER, PEGGY L. · 2010 to 2014
$11.0M
Advanced PET/CT Imaging for Improving Clinical TrialsU01CA148131 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E., LINDEN, HANNAH M · 2010 to 2019
$6.0M
PET to Measure Breast Cancer Bone Metastasis ResponseR01CA124573 · NCI · UNIVERSITY OF WASHINGTON · PI SPECHT, JENNIFER MARIE · 2007 to 2011
$1.8M
NCI NIH HHS CA124573NCI NIH HHS CA138293NCI NIH HHS CA148131NCI NIH HHS CA42045NCI NIH HHS P30 CA015704NCI NIH HHS P50 CA138293
6 · The paper itself

Abstract

Advances in our ability to assay molecular processes, including gene expression, protein expression, and molecular and cellular biochemistry, have fueled advances in our understanding of breast cancer biology and have led to the identification of new treatments for patients with breast cancer. The ability to measure biologic processes without perturbing them in vivo allows the opportunity to better characterize tumor biology and to assess how biologic and cytotoxic therapies alter critical pathways of tumor response and resistance. By accurately characterizing tumor properties and biologic processes, molecular imaging plays an increasing role in breast cancer science, clinical care in diagnosis and staging, assessment of therapeutic targets, and evaluation of responses to therapies. This review describes the current role and potential of molecular imaging modalities for detection and characterization of breast cancer and focuses primarily on radionuclide-based methods.

Indexed as

Breast NeoplasmsFemaleHumansMammographyMolecular ImagingPhotonsPositron-Emission TomographyRadioisotopesRadioisotopes

Identifiers

PMID22423895
PMCPMC3446362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.